MRI Study of Brain Activity in Healthy Adults and Individuals With Parkinsonism and Rapid Eye Movement Disorder.
|ClinicalTrials.gov Identifier: NCT01547481|
Recruitment Status : Completed
First Posted : March 7, 2012
Last Update Posted : May 17, 2018
|Condition or disease|
|Movement Disorders (Incl Parkinsonism) Tremor Familial Essential, 1 REM Sleep Behavior Disorder|
|Study Type :||Observational|
|Actual Enrollment :||50 participants|
|Official Title:||Statistical Mapping of the Brain in Progressive Supranuclear Palsy, Essential Tremor, Parkinson Disease, Parkinsonism, and REM Behavior Disorder|
|Study Start Date :||December 2011|
|Actual Primary Completion Date :||December 31, 2015|
|Actual Study Completion Date :||December 31, 2015|
Parkinson's Disease Cohort
Individuals Diagnosed with Parkinson's Disease
Essential Tremor cohort
Individuals Diagnosed with Essential Tremor
Rapid Eye Movement Disorder Cohort
Individuals Diagnosed with Rapid-Eye Movement Behavior Disorder (RBD). Eligible individuals will have been diagnosed with RBD based on a sleep study prior to entering the study. This study does not pay for or support a sleep study.
Healthy Control group
Individuals are healthy, without a known neurologic disease.
Progressive Supranuclear Palsy Cohort
Individuals diagnosed with Progressive Supranuclear Palsy (PSP).
Parkinsonism - Undifferentiated
Individuals with any form of Parkinsonism, not meeting any of the above cohorts.
- fMRI compared between cohorts [ Time Frame: one time at initial visit ]Studying resting brain activity between healthy adults, participants with Parkinson's and participants with REM Behavior Disorder.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01547481
|United States, Alabama|
|University of Alabama at Birmingham|
|Birmingham, Alabama, United States, 35294|
|Principal Investigator:||Frank Skidmore, MD||University of Alabama at Birmingham|