Insulin Variance Throughout the Day
Recruitment status was: Recruiting
|Study Design:||Observational Model: Case-Only
Time Perspective: Prospective
|Official Title:||Testing Whether Insulin Resistance Varies Throughout a Day A Pilot Study|
- Evaluating change in insulin sensitivity between morning and evening [ Time Frame: 24 hours ] [ Designated as safety issue: No ]This study designed to determine whether a person's sensitivity to their own insulin varies from the morning to the evening. The test is useful in the diagnosis of diabetes, and pre diabetes. Oral Glucose Testing provides details about how quickly glucose is absorbed into the bloodstream for use by body cells as energy. The rate of glucose clearance depends on the amount of glucose consumed. Once the participant drink a glucose-rich beverage, Blood will be drawn at different points and tested to see how effective the body breaks down metabolizes blood glucose.
Biospecimen Retention: Samples Without DNA
|Study Start Date:||March 2012|
|Estimated Study Completion Date:||March 2013|
|Estimated Primary Completion Date:||March 2013 (Final data collection date for primary outcome measure)|
Healthy participants between the age of 18 and 70 years with fasting blood sugar that is between normal and diabetes.
Study visit 1: about 16 hours - you will come to this visit fasting.
You will have an oral glucose tolerance test which takes about 3 ½ hours. An IV line will be placed in your arm vein for blood draw purposes and will remain there throughout the testing. A blood sample will be drawn 15 minutes and just before you will drink a sugar solution consisting of 75 grams of glucose. Blood will be drawn at specific times after you consume the drink.
You will have a second oral glucose tolerance test which takes about 3 ½ hours. An IV line will be placed in your arm vein for blood draw purposes and will remain there throughout the testing. A blood sample will be drawn 15 minutes and just before you will drink a sugar solution. Blood will be drawn at specific times after you consume the drink.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01546545
|United States, Louisiana|
|Pennington Biomedical Research Center|
|Baton Rouge, Louisiana, United States, 70808|
|Principal Investigator:||Jeffrey Gimble, MD, PhD||Pennington Biomedical Research Center|