Effect of Preop Nutritional Status on Outcomes of Staged Bilateral Total Knee Arthroplasty
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|ClinicalTrials.gov Identifier: NCT01545362|
Recruitment Status : Completed
First Posted : March 6, 2012
Last Update Posted : January 12, 2017
|Condition or disease||Intervention/treatment|
|Arthritis||Procedure: Total knee arthroplasty|
Association of malnutrition with postoperative complications after TKA has been reported in the form of increased rate of periprosthetic infection, longer hospital stay, etc. Reduced serum albumin and total lymphocyte count are commonly used to define malnutrition.
The goal was to evaluate the impact of the nutritional status on the outcomes of primary staged bilateral TKAs performed one-week apart during two separate hospitalizations.
Fifty consecutive patients with mean age of 67 years, mean BMI of 28.9 and 2.3 mean ASA score were followed for one year.
Prior to the first surgery 32% had a TLC <1500 cells/mm3 and 84% had a SA <3.5 g/dL. Before the second surgery 62% had a reduced TLC and all but one had a reduced SA.
Nine patients had a total of 12 perioperative blood transfusions (2 after the first surgery and 10 after the second surgery). The average length of stay was 3 days after each TKA.
None of the patients with the lowest TLC or SA before the first or the second stage had a revision.
Bilateral TKAs performed seven days apart in two separate hospitalizations is a safe and practical approach for qualified patients. The postoperative course was similar after each surgery. The preoperative nutritional status defined by TLC and SA did not influence the postoperative outcomes.
|Study Type :||Observational|
|Actual Enrollment :||50 participants|
|Official Title:||The Effect of Preop Nutritional Status on Outcomes of Staged Bilateral Total Knee Replacements Performed Within One Week|
|Study Start Date :||November 2011|
|Primary Completion Date :||November 2016|
|Study Completion Date :||November 2016|
Staged bilateral total knee arthroplasty
Patients that have bilateral total knee arthroplasty staged within one week
Procedure: Total knee arthroplasty
Total knee arthroplasty
- Blood loss until drain is pulled [ Time Frame: postoperatively ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01545362
|United States, Florida|
|Heekin Orthopedic Specialists|
|Jacksonville, Florida, United States, 32204|
|Principal Investigator:||R. David Heekin, M.D.||Heekin Institute for Orthopedic Research|