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Effects of Inspiratory Muscle Training on Dyspnea in Subjects With Chronic Obstructive Pulmonary Disease (IMT)

This study has been completed.
ClinicalTrials.gov Identifier:
First Posted: March 6, 2012
Last Update Posted: September 19, 2012
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Ministry of Health, France
Information provided by (Responsible Party):
University Hospital, Brest
The purpose of this study is to determinate whether inspiratory muscle training (IMT) associated with a conventional respiratory rehabilitation program is more effective than a conventional respiratory rehabilitation program alone,on Dyspnea in chronic obstructive pulmonary disease (COPD) subjects with a normal maximum inspiratory pressure (IP > 60 cmH2O).

Condition Intervention
Chronic Obstructive Pulmonary Disease Other: Inspiratory muscle training

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Supportive Care
Official Title: Effects of Inspiratory Muscle Training Combined With a Pulmonary Rehabilitation Program Versus a Program of Pulmonary Rehabilitation Alone on Dyspnea: a Randomized Trial

Resource links provided by NLM:

Further study details as provided by University Hospital, Brest:

Primary Outcome Measures:
  • Dyspnea measure [ Time Frame: 21 days ]
    Measure of changes in Mutidimentionnal Dyspnea Profile result questionnaire

Enrollment: 38
Study Start Date: October 2011
Study Completion Date: September 2012
Primary Completion Date: April 2012 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
No Intervention: standard
conventional respiratory rehabilitation
Experimental: IMT
Inspiratory muscle training and conventional respiratory rehabilitation
Other: Inspiratory muscle training
Inspiratory muscle training

Detailed Description:

Dyspnea is the main complaint of patients with COPD. Dyspnea is explained largely by the distension, objectified by measuring inspiratory capacity (IC), which places the diaphragm at a disadvantage to be effective, which raises the sensation of dyspnea.

Currently, inspiratory muscles training is recommended by the French-language Society of Pneumology, in case of an objective reduction of the strength of these muscles (corresponding to maximum inspiratory pressure <60 cm H20).


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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Patient with COPD
  • Hospitalized in the pulmonary rehabilitation unit in the hospital of Morlaix, with a 3 weeks pulmonary rehabilitation course

Exclusion Criteria:

  • Pneumonectomy, Lobectomy less than 6 months
  • Cardio-pulmonary anomaly
  • Max inspiratory pressure < 60 cm H2O
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01545011

Brest University Hospital
Brest, Brittany, France, 29200
Hospital of Morlaix
Morlaix, Brittany, France, 29600
Sponsors and Collaborators
University Hospital, Brest
Ministry of Health, France
  More Information

Responsible Party: University Hospital, Brest
ClinicalTrials.gov Identifier: NCT01545011     History of Changes
Other Study ID Numbers: RB 11.083 (EMI)
First Submitted: February 29, 2012
First Posted: March 6, 2012
Last Update Posted: September 19, 2012
Last Verified: September 2012

Keywords provided by University Hospital, Brest:
Inspiratory muscle training
Conventional respiratory rehabilitation
Dyspnea scale

Additional relevant MeSH terms:
Lung Diseases
Lung Diseases, Obstructive
Pulmonary Disease, Chronic Obstructive
Respiratory Aspiration
Respiratory Tract Diseases
Respiration Disorders
Signs and Symptoms, Respiratory
Signs and Symptoms
Pathologic Processes