Nutrition and Physical Exercise Study

This study has been completed.
Information provided by (Responsible Party):
Kantonsspital Winterthur KSW Identifier:
First received: February 23, 2012
Last updated: June 25, 2015
Last verified: June 2015
The purpose of this study is to investigate the effect of a combined treatment of nutritional therapy and physical exercise in palliative cancer out-patients. The investigators hypothesize that this combined intervention consisting of an increased energy- and protein intake and physical exercise level improves quality of life (QoL), functional and clinical status.

Condition Intervention
Gastrointestinal Cancer
Lung Cancer
Behavioral: Nutrition & physical exercise

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single Blind (Outcomes Assessor)
Primary Purpose: Supportive Care
Official Title: Influence of a Combined Intervention by Nutritional Support and Physical Exercise on Quality of Life in Cancer Out-patients Treated in Palliative Intention.

Resource links provided by NLM:

Further study details as provided by Kantonsspital Winterthur KSW:

Primary Outcome Measures:
  • Quality of life [ Time Frame: 3 months ] [ Designated as safety issue: No ]

Enrollment: 58
Study Start Date: March 2012
Study Completion Date: March 2015
Primary Completion Date: March 2015 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Nutrition & physical exercise Behavioral: Nutrition & physical exercise
Patients will be randomly assigned to intensive individual nutritional counselling including oral nutritional supplements and a specifically designed exercise program combining strength and balance training.
No Intervention: Control


Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Histologically or cytologically confirmed metastatic lung cancer or gastrointestinal cancer
  • WHO performance status 0, 1 or 2
  • Able to walk at least 100 meters independently without crutches or walking frame assessed by the treating physician on the basis of the patient's history and physical condition
  • Receiving palliative treatment

Exclusion Criteria:

  • Enteral and/or parenteral nutrition within 1 month previous to study participation
  • History of ileus within one month
  • Known brain metastases or symptomatic bone metastases
  • Psychiatric disorder precluding understanding of information on trial related topics and giving informed consent.
  • Any serious underlying medical condition which could impair the ability of the patient to participate in the trial
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01540968

Kantonsspital Winterthur
Winterthur, Switzerland, 8401
Sponsors and Collaborators
Kantonsspital Winterthur KSW
Study Chair: Peter E. Ballmer, Prof. Dr. Kantonsspital Winterthur KSW
  More Information

No publications provided

Responsible Party: Kantonsspital Winterthur KSW Identifier: NCT01540968     History of Changes
Other Study ID Numbers: KEK-ZH-Nr. 2011-0447, KFS-2833-08-2011
Study First Received: February 23, 2012
Last Updated: June 25, 2015
Health Authority: Switzerland: Ethikkommission

Additional relevant MeSH terms:
Gastrointestinal Neoplasms
Digestive System Diseases
Digestive System Neoplasms
Gastrointestinal Diseases
Neoplasms by Site processed this record on November 27, 2015