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Mean Platelet Volume and TXA2 Levels in Patients With Polycystic Ovary Syndrome (PCOS)

This study has been completed.
Information provided by (Responsible Party):
AGUNCO Obstetrics and Gynecology Centre Identifier:
First received: February 21, 2012
Last updated: February 23, 2012
Last verified: February 2012
Polycystic ovary syndrome (PCOS)is closely associated with insulin resistance and hyperinsulinemia as well as with increased incidence in diabetes, hypertension, dyslipidemia and atherosclerosis. Indeed, subjects with PCOS were reported to carry an increased long-term cardiovascular risk, among others. Aiming to correlate the mean platelet volume, the thromboxane A2 level and the PCOS, an observational study was planned. Clinical evaluation of metabolic outcomes in PCOS patients is compared to a placebo group.

Polycystic Ovary Syndrome

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective

Resource links provided by NLM:

Further study details as provided by AGUNCO Obstetrics and Gynecology Centre:

Primary Outcome Measures:
  • Mean platelet volume
  • Thromboxane A2

PCOS patients
Healthy volunteers


Ages Eligible for Study:   20 Years to 35 Years   (Adult)
Sexes Eligible for Study:   Female
Sampling Method:   Non-Probability Sample
Study Population

Inclusion Criteria:

  • Women fulfilled two out of three diagnostic criteria for PCOS

Exclusion Criteria:

  • Pre-existing secondary endocrine disorders
  • History of hypertension, diabetes mellitus or cardiovascular disorders
  • Pharmacologic treatment in the last 6 months before entering the study.
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Please refer to this study by its identifier: NCT01538602

Istituto di Patologia Ostetrica e Ginecologica
Catania, Italy
Sponsors and Collaborators
AGUNCO Obstetrics and Gynecology Centre
  More Information

Responsible Party: AGUNCO Obstetrics and Gynecology Centre Identifier: NCT01538602     History of Changes
Other Study ID Numbers: MPV_PCOS
Study First Received: February 21, 2012
Last Updated: February 23, 2012

Keywords provided by AGUNCO Obstetrics and Gynecology Centre:
cardiovascular disorders

Additional relevant MeSH terms:
Polycystic Ovary Syndrome
Pathologic Processes
Ovarian Cysts
Ovarian Diseases
Adnexal Diseases
Genital Diseases, Female
Gonadal Disorders
Endocrine System Diseases processed this record on May 25, 2017