Trial record 8 of 36 for:    Bell's Palsy

Microbiologic Findings of Acute Facial Palsy in Children

This study has been completed.
Helsinki University Central Hospital
Information provided by (Responsible Party):
Mervi Kanerva, Helsinki University Identifier:
First received: February 18, 2012
Last updated: February 22, 2012
Last verified: February 2012

Objective: Microbiologic etiologies of facial palsy in children were investigated.

Study design: Prospective clinical study. Methods: Forty-six children aged 0-16 years with facial palsy comprised the study group. Paired serum samples and cerebrospinal fluid were tested to find indications (antibodies, growth of the microbe, or nucleic acids) of microbes putatively associated with facial palsy. The microbes tested were herpes simplex virus-1 and -2, varicella-zoster virus, human herpesvirus-6, Mycoplasma pneumoniae, Borrelia burgdorferi, influenza A and B-, picorna-, cytomegalo-, parainfluenza-, respiratory syncytial-, coxsackie B5-, adeno-, and enteroviruses, Chlamydia psittaci, and Toxoplasma gondii. Besides the routine tests in clinical practice, serum and cerebrospinal fluid samples were tested with a highly sensitive microarray assay for DNA of herpes simplex virus-1 and -2, human herpesvirus-6A , -6B, -7, Epstein-Barr-, cytomegalo-, and varicella-zoster viruses.

Facial Paralysis

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Microbiologic Findings of Acute Facial Palsy in Children

Resource links provided by NLM:

Further study details as provided by Helsinki University:

Enrollment: 46
Study Start Date: May 2007
Study Completion Date: August 2009
Primary Completion Date: August 2009 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   up to 16 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Tertiary university Hospital, children 0-16 years old

Inclusion Criteria:

  • Age 0-16
  • Facial palsy
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  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Mervi Kanerva, MD, PhD, Helsinki University Identifier: NCT01537952     History of Changes
Other Study ID Numbers: 230419 
Study First Received: February 18, 2012
Last Updated: February 22, 2012
Health Authority: Finland: Ethics Committee

Keywords provided by Helsinki University:
facial paralysis, facial nerve, borreliosis, Bell's palsy

Additional relevant MeSH terms:
Bell Palsy
Facial Paralysis
Cranial Nerve Diseases
DNA Virus Infections
Disease Attributes
Facial Nerve Diseases
Herpesviridae Infections
Mouth Diseases
Nervous System Diseases
Neurologic Manifestations
Pathologic Processes
Signs and Symptoms
Stomatognathic Diseases
Virus Diseases processed this record on May 26, 2016