Microbiologic Findings of Acute Facial Palsy in Children
|ClinicalTrials.gov Identifier: NCT01537952|
Recruitment Status : Completed
First Posted : February 23, 2012
Last Update Posted : February 23, 2012
Objective: Microbiologic etiologies of facial palsy in children were investigated.
Study design: Prospective clinical study. Methods: Forty-six children aged 0-16 years with facial palsy comprised the study group. Paired serum samples and cerebrospinal fluid were tested to find indications (antibodies, growth of the microbe, or nucleic acids) of microbes putatively associated with facial palsy. The microbes tested were herpes simplex virus-1 and -2, varicella-zoster virus, human herpesvirus-6, Mycoplasma pneumoniae, Borrelia burgdorferi, influenza A and B-, picorna-, cytomegalo-, parainfluenza-, respiratory syncytial-, coxsackie B5-, adeno-, and enteroviruses, Chlamydia psittaci, and Toxoplasma gondii. Besides the routine tests in clinical practice, serum and cerebrospinal fluid samples were tested with a highly sensitive microarray assay for DNA of herpes simplex virus-1 and -2, human herpesvirus-6A , -6B, -7, Epstein-Barr-, cytomegalo-, and varicella-zoster viruses.
|Condition or disease|
|Study Type :||Observational|
|Actual Enrollment :||46 participants|
|Official Title:||Microbiologic Findings of Acute Facial Palsy in Children|
|Study Start Date :||May 2007|
|Primary Completion Date :||August 2009|
|Study Completion Date :||August 2009|