Try our beta test site
IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more...

Vaginal or Laparoscopic Hysterectomy, Persistent Postsurgical Pain

This study has been completed.
Information provided by (Responsible Party):
Arvi Yli-Hankala, Tampere University Hospital Identifier:
First received: January 10, 2012
Last updated: October 8, 2013
Last verified: October 2013
Previous studies have shown that chronic pain after hysterectomy is common. The aim of this study is to investigate the incidence of chronic pain after vaginal or laparoscopic hysterectomy for benign reasons. The aim of this prospective study is also to study the role of anesthetics, surgery and other possible predictors for pain 6 months after hysterectomy.

Condition Intervention
Chronic Postsurgical Pain
Procedure: vaginal or laparoscopic hysterectomy

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Chronic Pain After Vaginal or Laparoscopic Hysterectomy for Benign Conditions

Resource links provided by NLM:

Further study details as provided by Arvi Yli-Hankala, Tampere University Hospital:

Primary Outcome Measures:
  • Presence of persistent postsurgical pain as measured at 6 months after surgery. [ Time Frame: five years ]

Secondary Outcome Measures:
  • Severity, location, characteristics of persistent postsurgical pain. [ Time Frame: five years ]
  • Effect of postsurgical pain on activity, sleep. [ Time Frame: five years ]

Estimated Enrollment: 225
Study Start Date: April 2009
Study Completion Date: October 2013
Primary Completion Date: October 2013 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Patient who previously underwent vaginal or laparoscopic hysterectomy
Procedure: vaginal or laparoscopic hysterectomy
vaginal hysterectomy or laparoscopic hysterectomy


Ages Eligible for Study:   18 Years to 69 Years   (Adult, Senior)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Women who undergo vaginal or laparoscopic hysterectomy for benign conditions.

Inclusion Criteria:

  • Patients who undergo vaginal or laparoscopic hysterectomy for benign conditions
  • Age 18-69 years
  • Gender: female
  • ASA status 1-3

Exclusion Criteria:

  • Body Mass Index over 35
  • Diabetes mellitus
  • Liver disease
  • Preoperative use of opioids
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01537731

Tampere University Hospital
Tampere, Finland, 33521
Sponsors and Collaborators
Tampere University Hospital
  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Arvi Yli-Hankala, professor, Tampere University Hospital Identifier: NCT01537731     History of Changes
Other Study ID Numbers: R08031M R09003
Study First Received: January 10, 2012
Last Updated: October 8, 2013 processed this record on May 25, 2017