MR-Evaluation of Renal Function-After-Pancreas-transplantation (MERFAP)
Recruitment status was Not yet recruiting
The purpose of this study is to evaluate the beneficial effect of pancreas transplantation for long term kidney function in patients undergoing single-pancreas transplantation.
|Study Design:||Observational Model: Case-Only
Time Perspective: Prospective
|Official Title:||MR-Evaluation of Renal Function-After-Pancreas-transplantation|
- Kidney function [ Time Frame: Within 3 years ] [ Designated as safety issue: No ]Improvements in kidney function (GFR) and proteinuria after pancreas transplantation.
- Kidney hemodynamics and oxygenation [ Time Frame: Within 3 years ] [ Designated as safety issue: No ]Improvements in renal blood flow and kidney tissue oxygenation after pancreas transplantation.
|Study Start Date:||February 2012|
|Estimated Study Completion Date:||August 2015|
|Estimated Primary Completion Date:||February 2015 (Final data collection date for primary outcome measure)|
Patients with pancreastransplantation
All patients undergoing pancreas transplantation.
Renal failure in patients who have performed a pancreas transplantation is a hazard for the outcome for these patients. The beneficial effect of pancreas transplantation for renal function is not clear. It is of major importance to early find patients who develops a decrease in renal function and start treatment early and closely monitor these patients in order to avoid further deteriorating renal function. In order to achieve this, there is a need for a easy, fast and sensitive method to evaluate renal function. In this study the investigators plan to use the non-invasive MR to evaluate changes in renal function.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01537445
|University Hospital||Not yet recruiting|
|Uppsala, Sweden, 75185|
|Contact: Per Liss, MD, PhD. +46186110000 email@example.com|
|Study Director:||Per Liss, MD, PhD.||Uppsala University, Uppsala, Sweden|