MR-Evaluation of Renal Function-After-Pancreas-transplantation (MERFAP)
The purpose of this study is to evaluate the beneficial effect of pancreas transplantation for long term kidney function in patients undergoing single-pancreas transplantation.
|Study Design:||Observational Model: Case-Only
Time Perspective: Prospective
|Official Title:||MR-Evaluation of Renal Function-After-Pancreas-transplantation|
- Kidney function [ Time Frame: Within 3 years ] [ Designated as safety issue: No ]Improvements in kidney function (GFR) and proteinuria after pancreas transplantation.
- Kidney hemodynamics and oxygenation [ Time Frame: Within 3 years ] [ Designated as safety issue: No ]Improvements in renal blood flow and kidney tissue oxygenation after pancreas transplantation.
|Study Start Date:||February 2012|
|Estimated Study Completion Date:||August 2015|
|Estimated Primary Completion Date:||February 2015 (Final data collection date for primary outcome measure)|
Patients with pancreastransplantation
All patients undergoing pancreas transplantation.
Renal failure in patients who have performed a pancreas transplantation is a hazard for the outcome for these patients. The beneficial effect of pancreas transplantation for renal function is not clear. It is of major importance to early find patients who develops a decrease in renal function and start treatment early and closely monitor these patients in order to avoid further deteriorating renal function. In order to achieve this, there is a need for a easy, fast and sensitive method to evaluate renal function. In this study the investigators plan to use the non-invasive MR to evaluate changes in renal function.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01537445
|University Hospital||Not yet recruiting|
|Uppsala, Sweden, 75185|
|Contact: Per Liss, MD, PhD. +46186110000 firstname.lastname@example.org|
|Study Director:||Per Liss, MD, PhD.||Uppsala University, Uppsala, Sweden|