We updated the design of this site on September 25th. Learn more.

A Comparison Study of the Tensile Strength of Sutures Used in Dermatologic Surgery on the Day of Suture Removal, Following Wound Care With Two Different Products

This study has been completed.

Sponsor:

ClinicalTrials.gov Identifier:

NCT01533675

First Posted: February 15, 2012

Last Update Posted: May 10, 2017

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.

Information provided by (Responsible Party):

Keyvan Nouri, University of Miami

Purpose

Sutures are an integral part of surgery and available materials are diverse, as are the options for post-procedure care. Both saline and hydrogen peroxide are commonly used cleansing agents. This study aims to compare the effect of saline and hydrogen peroxide on the tensile strength of 4-0 nylon sutures following removal from a cutaneous surgical wound.

Condition	Intervention
Sutured Wounds	Other: Hydrogen peroxide Other: Saline


Study Type:	Interventional
Study Design:	Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double (Participant, Care Provider) Primary Purpose: Treatment
Official Title:	A Comparison Study of the Tensile Strength of Sutures Used in Dermatologic Surgery on the Day of Suture Removal, Following Wound Care With Two Different

Resource links provided by NLM:

MedlinePlus related topics: Wounds and Injuries

Drug Information available for: Hydrogen peroxide

U.S. FDA Resources

Further study details as provided by Keyvan Nouri, University of Miami:

Primary Outcome Measures:

Tensile strength of 4-0 nylon sutures [ Time Frame: 14 days ]
The tensile strength was defined as the force required to break the suture, with breaking strength as the maximum strength that a material can withstand when subjected to an applied load, without taking into consideration the cross sectional area. The strength of the sutures was measured using a tensometer.


Enrollment:	40
Study Start Date:	May 2010
Study Completion Date:	August 2011
Primary Completion Date:	August 2011 (Final data collection date for primary outcome measure)

Arms	Assigned Interventions
Experimental: Hydrogen peroxide	Other: Hydrogen peroxide Once daily topical application of 3% hydrogen peroxide using a cotton-tipped applicator
Active Comparator: Saline	Other: Saline Once daily topical application of normal saline, using a cotton-tipped applicator

Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:	18 Years and older (Adult, Senior)
Sexes Eligible for Study:	All
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

Subject is willing to comply with the informed consent procedures
Subject's wound is on the body or scalp
Subject will be able to come to the clinic for suture removal on day 14

Exclusion Criteria:

Subject is less than 18 years of age
Subject's wound was not closed with 4-0 nylon sutures
Subject's wound is on the face
Subject plans to apply other topicals to the area under study
Subject's suture is removed before or after day 14

Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01533675

Locations


United States, Florida
University of Miami Hospital and Clinics/Sylvester Comprehensive Cancer Center
Miami, Florida, United States, 33136

Sponsors and Collaborators

University of Miami

More Information

Publications:

Snyder CC. On the history of the suture. Plast Reconstr Surg. 1976 Oct;58(4):401-6.

Hochberg J, Meyer KM, Marion MD. Suture choice and other methods of skin closure. Surg Clin North Am. 2009 Jun;89(3):627-41. doi: 10.1016/j.suc.2009.03.001. Review.


Responsible Party:	Keyvan Nouri, Keyvan Nouri, M.D Professor of Dermatology, Ophthalmology & Otolaryngology, Chief of Dermatology Servic, University of Miami
ClinicalTrials.gov Identifier:	NCT01533675 History of Changes
Other Study ID Numbers:	# 20100301
First Submitted:	February 10, 2012
First Posted:	February 15, 2012
Last Update Posted:	May 10, 2017
Last Verified:	May 2017

Keywords provided by Keyvan Nouri, University of Miami:


suture, tensile strength, wound care, saline, hydrogen peroxide, skin closure, wounds, wound healing, wound cleansing, antiseptics

Additional relevant MeSH terms:


Wounds and Injuries Hydrogen Peroxide Anti-Infective Agents, Local Anti-Infective Agents

To Top