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Susceptibility to Pathological Gambling

This study is currently recruiting participants.
See Contacts and Locations
Verified July 2016 by Jon Grant, University of Chicago
Information provided by (Responsible Party):
Jon Grant, University of Chicago Identifier:
First received: August 30, 2011
Last updated: July 28, 2016
Last verified: July 2016
The goal of this study is to assess the risk factors for the development of pathological gambling.

Condition Intervention
Pathological Gambling Behavioral: Mindfulness Behavioral: Cognition

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Prevention
Official Title: Susceptibility to Pathological Gambling

Resource links provided by NLM:

Further study details as provided by Jon Grant, University of Chicago:

Primary Outcome Measures:
  • Structured Clinical Interview for Pathological Gambling (SCI-PG) [ Time Frame: Up to 3 years ]

    The SCI-PG is a validated and reliable scale assessing the presence of DSM-IV criteria for pathological gambling. The number of criteria met for PG is added for a total score and those meeting 5 or more criteria have DSM-IV pathological gambling.

    Subjects are expected to be followed for the duration of the 3 year study.

    Diagnostic criteria for pathological gambling every 3 months for the length of the study

Estimated Enrollment: 600
Study Start Date: November 2008
Estimated Study Completion Date: September 2017
Estimated Primary Completion Date: September 2017 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
No Intervention: Control
Active Comparator: Mindfulness
Mindfulness activity and psychoeducation
Behavioral: Mindfulness
Subjects receive mindfulness training
Other Name: Training
Active Comparator: Cognition
Cognitive training and psychoeducation
Behavioral: Cognition
Subject receive cognitive training
Other Name: Training

Detailed Description:
This study will track up to 600 young adults (ages 18 to 29) for a two-year period, collecting variables such as gambling behavior, drug and alcohol use, psychiatry and medical history, family history, impulsivity, quality of life, self-esteem, and cognition. For some individuals who meet criteria as being impulsive, they will be randomized to receive an intervention to help reduce their impulsivity.

Ages Eligible for Study:   18 Years to 29 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Ability to understand the procedures and provide written consent
  • Gambled at least 5 times in the past year
  • Between the ages of 18 and 29 at intake

Exclusion Criteria:

  • Inability to understand the procedures and provide written consent
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01528982

Contact: Eric Leppink, BA 773-834-3778

United States, Illinois
University of Chicago Recruiting
Chicago, Illinois, United States, 60637
Contact: Jon E Grant, JD, MD, MPH    773-834-1325   
Contact: Eric Leppink, BA    773-834-3778   
Principal Investigator: Jon E Grant, JD, MD, MPH         
Sponsors and Collaborators
University of Chicago
Principal Investigator: Jon E Grant, JD, MD, MPH University of Chicago, Department of Psychiatry
  More Information

Responsible Party: Jon Grant, Profesor of Psychiatry, University of Chicago Identifier: NCT01528982     History of Changes
Other Study ID Numbers: 0811S53121
Study First Received: August 30, 2011
Last Updated: July 28, 2016

Additional relevant MeSH terms:
Disease Susceptibility
Disease Attributes
Pathologic Processes
Disruptive, Impulse Control, and Conduct Disorders
Mental Disorders processed this record on September 21, 2017