Tart Cherries and Melatonin Content
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|ClinicalTrials.gov Identifier: NCT01528202|
Recruitment Status : Completed
First Posted : February 7, 2012
Last Update Posted : February 7, 2012
|Condition or disease||Intervention/treatment||Phase|
|Sleep||Dietary Supplement: Cherry juice Dietary Supplement: Fruit juice cordial||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||20 participants|
|Intervention Model:||Crossover Assignment|
|Masking:||Triple (Participant, Investigator, Outcomes Assessor)|
|Official Title:||Effect of Tart Cherry Juice (Prunus Cerasus) on Melatonin Levels and Sleep Quality|
|Study Start Date :||April 2010|
|Actual Primary Completion Date :||February 2011|
|Actual Study Completion Date :||June 2011|
No Intervention: Baseline placebo
measures taken before administration of placebo
Placebo Comparator: Placebo
Placebo intervention given after 'baseline placebo' arm
Dietary Supplement: Fruit juice cordial
fruit flavoured juice concentrate
Other Name: Apple and blackcurrent squash (0164 9338). Sainsbry's Supermarkets Ltd.
No Intervention: baseline cherry juice
measures taken before the cherry juice intervention
Experimental: cherry juice
trial where cherry juice is taken following the 'baseline cherry juice' arm
Dietary Supplement: Cherry juice
30 mLs preceding morning meal and 30 mLs preceding evening meal each day for 7 days.
Other Name: CherryActive concentrate
- urinary 6-sulphatoxymelatonin [ Time Frame: continually for 48 hours ]urinary 6-sulphatoxymelatonin is the primary metabolite of melatonin and provides a sarrogate marker of melatonin metabolism. By measuring over a 48 h period it is possible to examine the circadian rhythm of melatonin.
- Sleep quality [ Time Frame: continually throughout the duration of the study ]Acti watches quantitively measure sleep and activity of participants, whereas slep recall provides a retrospective and subjective m,easure of sleep quality.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01528202
|Newcastle upon Tyne, Tyne and Wear, United Kingdom, NE1 8ST|
|Principal Investigator:||Glyn Howatson, PhD||Northumbria University|