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Strategies to Improve Asthma and Treatment of Asthma in Canadians

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01525381
First Posted: February 2, 2012
Last Update Posted: March 31, 2016
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Ottawa Hospital Research Institute
  Purpose
Our study will enroll 644 randomly-selected Canadians who have been diagnosed with asthma by a physician within the previous five years. It will be determined what diagnostic tests were initially performed to make this diagnosis. Participants will undergo lung function testing over 6-8 weeks to determine their respiratory status and to confirm they have asthma. Participants may be followed up to one year depending on their test results.

Condition
Asthma

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Strategies to Improve Diagnosis and Treatment of Asthma in Canadians

Further study details as provided by Ottawa Hospital Research Institute:

Enrollment: 701
Study Start Date: November 2011
Study Completion Date: March 2016
Primary Completion Date: April 2015 (Final data collection date for primary outcome measure)
  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years to 100 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Canadians diagnosed with Asthma and 18 years of age and older.
Criteria

Inclusion Criteria:

  1. Patient must have a recent diagnosis of asthma by a physician. Diagnosis of asthma must have occurred within 5 years prior to entry into the study.
  2. Patient must be at least 18 years old.

Exclusion Criteria:

  1. Patients in whom methacholine challenge is contraindicated

    • Patients using chronic oral prednisone.
    • Patients with heart attack or stroke within three previous months, and those with known aortic or cerebral aneurysms.
    • Pregnant patients (unknown effect of methacholine on the fetus) and breastfeeding patients (unknown whether methacholine is excreted in breast milk).
  2. Patients unable to provide informed consent.
  3. Patients not able to perform spirometry and/or methacholine challenge testing.
  4. Patients who have a greater than 10 pack-year smoking history (this will exclude patients with possible COPD).
  5. Patients who currently have active pulmonary Tuberculosis
  6. Patients who have had eye surgery in the past 3 months or who have a detached retina
  7. Patients involved in another interventional asthma study
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01525381


Locations
Canada, Ontario
Ottawa Hospital
Ottawa, Ontario, Canada, K1H 8L6
Sponsors and Collaborators
Ottawa Hospital Research Institute
Investigators
Principal Investigator: Shawn Aaron, MD Ottawa Hosptial Research Institute
  More Information

Responsible Party: Ottawa Hospital Research Institute
ClinicalTrials.gov Identifier: NCT01525381     History of Changes
Other Study ID Numbers: 2011-221
First Submitted: January 31, 2012
First Posted: February 2, 2012
Last Update Posted: March 31, 2016
Last Verified: March 2016

Additional relevant MeSH terms:
Asthma
Bronchial Diseases
Respiratory Tract Diseases
Lung Diseases, Obstructive
Lung Diseases
Respiratory Hypersensitivity
Hypersensitivity, Immediate
Hypersensitivity
Immune System Diseases