Study of Association Between Maternal Uric Acid , Maternal and Fetal Outcome in Pregnant Women With Hypertension
![]() |
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. |
ClinicalTrials.gov Identifier: NCT01523327 |
Recruitment Status
: Unknown
Verified January 2012 by nermin marzouk agaibi, Ain Shams Maternity Hospital.
Recruitment status was: Recruiting
First Posted
: February 1, 2012
Last Update Posted
: February 1, 2012
|
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
Condition or disease | Intervention/treatment |
---|---|
Uric Acid and Hypertension in Pregnancy | Other: measuring protein creatinin ratio,serum uric acid |
Study Type : | Observational |
Estimated Enrollment : | 80 participants |
Time Perspective: | Cross-Sectional |
Official Title: | Association of Maternal Uric Acid With Maternal Condition and Fetal Outcome in Pregnant Women With Hypertension |
Study Start Date : | October 2011 |
Actual Primary Completion Date : | November 2011 |
Estimated Study Completion Date : | October 2012 |

Group/Cohort | Intervention/treatment |
---|---|
A
40 pregnant Women with hypertension who have uric acid level more than 6 mg per dL.
|
Other: measuring protein creatinin ratio,serum uric acid
A non-deproteinized Jaffe reaction is employed to measure creatinine and urinary protein measured by an automated colorimetric assay using pyrogallol red and sodium molybdate. Measuring of serum uric acid by(2,4,6-tribromo-3-hydroxybenzoic acid)TBHBA by uricase method. |
B
40 pregnant women with hypertension who have uric acid level less than 6 mg per dl.
|
Other: measuring protein creatinin ratio,serum uric acid
A non-deproteinized Jaffe reaction is employed to measure creatinine and urinary protein measured by an automated colorimetric assay using pyrogallol red and sodium molybdate. Measuring of serum uric acid by(2,4,6-tribromo-3-hydroxybenzoic acid)TBHBA by uricase method. |

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study: | 18 Years to 40 Years (Adult) |
Sexes Eligible for Study: | Female |
Accepts Healthy Volunteers: | No |
Sampling Method: | Probability Sample |
Inclusion Criteria:
- Age:18-40 years old
- Gestational age:28-42 weeks gestation singleton pregnancy of living fetus
- Non smoker
Exclusion Criteria:
- women who refuse the study
- Any medical or obstetric disorders especially D.M.,renal disease,hepatic, cardiac disorders or gout arthritis, other than hypertension if present.
- Previously elevated uric acid level.
- Hemolytic or sickle cell anemia,urinary tract infection.
- Use of diuretics or anti-inflammatory drugs.

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01523327
Contact: Nermin marzouk touma, M.B.,B.Ch | 01222740182 ext 002 | nermindave@gmail.com | |
Contact: nermin Marzouk touma, M.B.,B.Ch | 0862636607 ext 002 | nermindave@gmail.com |
Egypt | |
Ain shams maternity hospital | Recruiting |
Cairo, Egypt, 11117 | |
Principal Investigator: nermin marzouk touma, M.B.,B.Ch |
Study Director: | Mohamed Saeedeldin Elsafty, assistant lecture | Ain Shams Maternity Hospital |
Additional Information:
Publications of Results:
Responsible Party: | nermin marzouk agaibi, Nermin Marzouk Agaibi, Ain Shams Maternity Hospital |
ClinicalTrials.gov Identifier: | NCT01523327 History of Changes |
Other Study ID Numbers: |
ainshamsMH |
First Posted: | February 1, 2012 Key Record Dates |
Last Update Posted: | February 1, 2012 |
Last Verified: | January 2012 |
Keywords provided by nermin marzouk agaibi, Ain Shams Maternity Hospital:
Uric acid |
Additional relevant MeSH terms:
Hypertension Hypertension, Pregnancy-Induced Pre-Eclampsia Vascular Diseases Cardiovascular Diseases Pregnancy Complications |
Uric Acid Antioxidants Molecular Mechanisms of Pharmacological Action Protective Agents Physiological Effects of Drugs |