Preventing Myocardial Ischemia by Preconditioning in Elective Operation for Abdominal Aortic Aneurysm
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|ClinicalTrials.gov Identifier: NCT01523262|
Recruitment Status : Unknown
Verified January 2015 by Nikolaj Eldrup, Aarhus University Hospital.
Recruitment status was: Recruiting
First Posted : February 1, 2012
Last Update Posted : January 14, 2015
Primary To investigate whether peripheral predonditioning induced by brief, intermittent constriction of blood supply to an arm can reduce the incidence of perioperative myocardial ischemia in patients operated electively for infrarenal aortic aneurysm.
Secondary To investigate the impact of peripheral preconditioning on perioperative inflammatory response.
To investigate whether peripheral preconditoning can protect against perioperative myocardial infarction and reduced cardiac pump function.
|Condition or disease||Intervention/treatment||Phase|
|Aortic Aneurysm||Procedure: preconditioning Procedure: Normal surgery, with sham intervention without inflating arm cuff||Phase 1|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||200 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Double (Participant, Investigator)|
|Official Title:||The Effect of Preconditioning to Prevent Perioperative Myocardial Ischemia in Elective Operation of Abdominal Aortic Aneurysm|
|Study Start Date :||January 2011|
|Estimated Primary Completion Date :||January 2015|
|Estimated Study Completion Date :||January 2016|
|Active Comparator: Preconditioning and normal treatment||
peripheral preconditioning induced by brief, intermittent constriction of blood supply to an arm
Placebo Comparator: normal treatment
|Procedure: Normal surgery, with sham intervention without inflating arm cuff|
- measurements of CKMB and Troponin T [ Time Frame: 30 days ]
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Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01523262
|Aarhus University Hospital, Skejby||Recruiting|
|Aarhus, Aarhus N, Denmark, 8200|
|Contact: Nikolaj Eldrup email@example.com|
|Sub-Investigator: Nikolaj Eldrup, MD, PHD|
|Aalborg Hospital||Not yet recruiting|
|Aalborg, Denmark, 9000|
|Contact: Troels F Pedersen, MD firstname.lastname@example.org|
|Principal Investigator: Troels F Pedersen, MD|