Preventing Myocardial Ischemia by Preconditioning in Elective Operation for Abdominal Aortic Aneurysm
Recruitment status was: Recruiting
Primary To investigate whether peripheral predonditioning induced by brief, intermittent constriction of blood supply to an arm can reduce the incidence of perioperative myocardial ischemia in patients operated electively for infrarenal aortic aneurysm.
Secondary To investigate the impact of peripheral preconditioning on perioperative inflammatory response.
To investigate whether peripheral preconditoning can protect against perioperative myocardial infarction and reduced cardiac pump function.
Procedure: Normal surgery, with sham intervention without inflating arm cuff
|Study Design:||Allocation: Randomized
Endpoint Classification: Safety Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Investigator)
Primary Purpose: Treatment
|Official Title:||The Effect of Preconditioning to Prevent Perioperative Myocardial Ischemia in Elective Operation of Abdominal Aortic Aneurysm|
- measurements of CKMB and Troponin T [ Time Frame: 30 days ] [ Designated as safety issue: No ]
|Study Start Date:||January 2011|
|Estimated Study Completion Date:||January 2016|
|Estimated Primary Completion Date:||January 2015 (Final data collection date for primary outcome measure)|
|Active Comparator: Preconditioning and normal treatment||
peripheral preconditioning induced by brief, intermittent constriction of blood supply to an arm
Placebo Comparator: normal treatment
|Procedure: Normal surgery, with sham intervention without inflating arm cuff|
Please refer to this study by its ClinicalTrials.gov identifier: NCT01523262
|Aarhus University Hospital, Skejby|
|Aarhus, Aarhus N, Denmark, 8200|
|Aalborg, Denmark, 9000|