Effect of the Salbutamol on Mechanical Properties of Respiratory System
|ClinicalTrials.gov Identifier: NCT01521572|
Recruitment Status : Unknown
Verified January 2012 by Gerusa Maritimo da Costa, Rio de Janeiro State University.
Recruitment status was: Recruiting
First Posted : January 30, 2012
Last Update Posted : February 2, 2012
|Condition or disease||Intervention/treatment|
|Smoking Airway Obstruction||Drug: Salbutamol sulphate|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||200 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Primary Purpose:||Basic Science|
|Official Title:||Effect of the Use of Salbutamol on the Mechanical Properties of the Respiratory System of Healthy Individuals, Smokers and COPD Patients|
|Study Start Date :||June 2011|
|Estimated Primary Completion Date :||January 2012|
|Estimated Study Completion Date :||September 2012|
Short-acting bronchodilator for use in humans released by the Ministry of Health, widely used worldwide for the treatment of chronic obstructive pulmonary disease.
Drug: Salbutamol sulphate
bronchodilator test, beta2-agonist, short-acting, six hours duration, 400 micrograms.
- Respiratory function test [ Time Frame: two o'clock ]Evaluation of pulmonary mechanics before and after salbutamol (short-acting bronchodilator) in healthy individuals, smokers and chronic obstructive pulmonary disease in stages: mild, moderate, severe and very severe according to GOLD criteria.
- Salbutamol [ Time Frame: twenty minutes ]In the bronchodilator test will be used 400 micrograms of beta2-agonist short-acting. They will be asked to exhale slowly until they can no longer expel more air from the lungs. To place the inhaler with a spacer between the lips, pressing them well, but no bite. Shortly thereafter start to breathe through the mouth and will be released a jet of 100 micrograms of the bronchodilator. Then they will hold their breath for 10 seconds. 3 puffs are made with 1 minute interval between each application.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01521572
|Contact: Agnaldo J Lopes, PhD||55+(21) firstname.lastname@example.org|
|Contact: Pedro L de Melo, PhD||55+(21) email@example.com|
|Laboratory biomedical instrumentation - State University of Rio de Janeiro||Recruiting|
|Rio de Janeiro, Brazil, 20550013|
|Principal Investigator: Gerusa M Costa, MSc|
|Principal Investigator:||Gerusa M Costa, MSc||State University of Rio de Janeiro|
|Study Director:||Pedro L Melo, PhD||Laboratory biomedical instrumentation|