Effect of the Salbutamol on Mechanical Properties of Respiratory System
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|ClinicalTrials.gov Identifier: NCT01521572|
Recruitment Status : Unknown
Verified January 2012 by Gerusa Maritimo da Costa, Rio de Janeiro State University.
Recruitment status was: Recruiting
First Posted : January 30, 2012
Last Update Posted : February 2, 2012
|Condition or disease||Intervention/treatment||Phase|
|Smoking Airway Obstruction||Drug: Salbutamol sulphate||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||200 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Primary Purpose:||Basic Science|
|Official Title:||Effect of the Use of Salbutamol on the Mechanical Properties of the Respiratory System of Healthy Individuals, Smokers and COPD Patients|
|Study Start Date :||June 2011|
|Estimated Primary Completion Date :||January 2012|
|Estimated Study Completion Date :||September 2012|
Short-acting bronchodilator for use in humans released by the Ministry of Health, widely used worldwide for the treatment of chronic obstructive pulmonary disease.
Drug: Salbutamol sulphate
bronchodilator test, beta2-agonist, short-acting, six hours duration, 400 micrograms.
- Respiratory function test [ Time Frame: two o'clock ]Evaluation of pulmonary mechanics before and after salbutamol (short-acting bronchodilator) in healthy individuals, smokers and chronic obstructive pulmonary disease in stages: mild, moderate, severe and very severe according to GOLD criteria.
- Salbutamol [ Time Frame: twenty minutes ]In the bronchodilator test will be used 400 micrograms of beta2-agonist short-acting. They will be asked to exhale slowly until they can no longer expel more air from the lungs. To place the inhaler with a spacer between the lips, pressing them well, but no bite. Shortly thereafter start to breathe through the mouth and will be released a jet of 100 micrograms of the bronchodilator. Then they will hold their breath for 10 seconds. 3 puffs are made with 1 minute interval between each application.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01521572
|Contact: Agnaldo J Lopes, PhD||55+(21) email@example.com|
|Contact: Pedro L de Melo, PhD||55+(21) firstname.lastname@example.org|
|Laboratory biomedical instrumentation - State University of Rio de Janeiro||Recruiting|
|Rio de Janeiro, Brazil, 20550013|
|Principal Investigator: Gerusa M Costa, MSc|
|Principal Investigator:||Gerusa M Costa, MSc||State University of Rio de Janeiro|
|Study Director:||Pedro L Melo, PhD||Laboratory biomedical instrumentation|