Comparison of Diagnostic Accuracy for Predicting Histology of Colorectal Lesions
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Comparison of Diagnostic Accuracy for Predicting Histology of Colorectal Lesions Using Magnifying Colonoscopy With Narrow Band Imaging, Indigo Carmine, and Acetic Acid Staining|
All the lesions will be removed endoscopically or surgically and examine histologically by an independent gastrointestinal pathologist.
Histological diagnosis is determined according to the World Health Organization (WHO) criteria. Pedunculated lesions are categorized according to Haggitt's classification.
|Study Start Date:||January 2009|
|Study Completion Date:||December 2010|
|Primary Completion Date:||December 2010 (Final data collection date for primary outcome measure)|
To compare the diagnostic accuracy of chromoendoscopy indigo carmine or acetic acid and NBI for differentiating neoplastic from non-neoplastic colorectal lesions, differentiating adenomas from carcinomas, and differentiating early carcinomas from invasive ones.
Included colorectal lesions consecutively distribute in a 1:1 ratio to 2 groups.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01521091
|Departments of Gastroenterology and Clinical Laboratory, Shanghai Renji Hospital, Shanghai Jiaotong University School of Medicine|
|Shanghai, China, 200001|
|Principal Investigator:||Xiaobo Li, MD. Ph.D||Departments of Gastroenterology and Clinical Laboratory, Shanghai Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai,China,Shanghai Institute of Digestive Disease, Shanghai, China|