Cognitive Training for Patients With Schizophrenia
This research on cognitive training addresses the following questions:
- Does cognitive training lead to improved cognition, functional abilities, psychiatric symptoms, treatment adherence, or quality of life in patients with psychoses?
- What are the neurocognitive and non-cognitive factors that predict good outcomes following cognitive rehabilitation? In addition to verbal learning and memory, immediate verbal memory, vigilance, and executive functioning, the cognitive training intervention attempted to improve prospective memory ability (i.e., the ability to remember to do things in the future, such as take medications or attend a doctor's appointment).
|Schizophrenia Schizoaffective Disorder Other Primary Psychotic Disorders||Behavioral: Cognitive Training||Phase 2|
|Study Design:||Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single Blind (Outcomes Assessor)
Primary Purpose: Treatment
|Official Title:||Cognitive Training for Patients With Schizophrenia|
- UCSD Performance-based Skills Assessment Total Score (Measures Functional Capacity) [ Time Frame: 3 months ]Performance-based measure of functional capacity in five domains: Communication, Finance, Recreation Planning, Transportation, and Household Chores Scale ranges from 0-100. Subscales are summed to yield the total score. Higher scores represent better performance.
- Hopkins Verbal Learning Test Percent Retained [ Time Frame: 3 months ]
Verbal list learning task with three learning trials and a delay trial. Percent retained refers to the percentage of items recalled at the delay trial, compared to the third learning trial.
Score ranges from 0-100. Higher scores represent better performance.
|Study Start Date:||September 2003|
|Study Completion Date:||August 2009|
|Primary Completion Date:||August 2009 (Final data collection date for primary outcome measure)|
Experimental: Cognitive Training
Cognitive training group
Behavioral: Cognitive Training
12-week compensatory cognitive training in group format
|No Intervention: Standard Pharmacotherapy|
Please refer to this study by its ClinicalTrials.gov identifier: NCT01521026
|United States, California|
|UCSD Outpatient Psychiatric Services|
|San Diego, California, United States, 92103|
|Principal Investigator:||Elizabeth W Twamley, PhD||UCSD|