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Pathological Subtrochanteric Fractures in 194 Patients

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ClinicalTrials.gov Identifier: NCT01520480
Recruitment Status : Completed
First Posted : January 30, 2012
Last Update Posted : January 31, 2012
Information provided by (Responsible Party):
Rudiger Weiss, Karolinska University Hospital

Brief Summary:
In this study, the investigators analyze a consecutive series of patients operated for pathological subtrochanteric femur fracture to describe survival and reoperation rates after surgery and to identify risk factors for death. Moreover, the investigators include a cohort of patients with non-pathological subtrochanteric fractures for comparison.

Condition or disease
Subtrochanteric Femur Fractures

Detailed Description:

The Scandinavian Sarcoma Group (SSG) has initiated a Skeletal Metastasis Register in 1999. The Register is a quality-control database which prospectively collects individual-based information on patients operated for skeletal metastases in the long bones and pelvis. Data on patient identity, age, sex, primary tumor, location of metastases, type of pathological fracture, and perioperative treatment were gathered. Information concerning surgical procedures such as method of fixation, type of implant, and postoperative complications are registered. Moreover, some clinical data such as pain levels (no, light, moderate, strong, or severe pain), pain medication use, mobility, and the Karnofsky performance score are recorded.

We will identify all patients surgically treated for pathological subtrochanteric femur fractures during 1999-2009.

The Stockholm Hip Fracture Group provides data on the reference group. During 2003, a consecutive series of patients with acute non-pathological subtrochanteric femur fractures treated in Stockholm were included in a prospective cohort study. The regional ethical review board located at the Karolinska Institutet approved the study (DNR 206/02).

The aim of this study is to analyze survival and reoperation rates of patients operated for pathological subtrochanteric femur fracture. We want compare those findings with a cohort of patients with non-pathological subtrochanteric fractures.

Study Type : Observational
Actual Enrollment : 281 participants
Observational Model: Case Control
Time Perspective: Retrospective
Official Title: Pathological Subtrochanteric Fractures in 194 Patients. A Comparison of Outcome After Surgical Treatment of Pathological and Non-pathological Fractures.
Study Start Date : January 1999
Primary Completion Date : January 2009
Study Completion Date : January 2009

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Non-pathological fracture
Non pathological subtrochanteric femur fractures
Pathological fracture
Pathological subtrochanteric fractures

Information from the National Library of Medicine

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Ages Eligible for Study:   15 Years and older   (Child, Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients with pathological subtrochanteric femur fractures.

Inclusion Criteria:

  • All patients with pathological subtrochanteric femur fractures register in the Scandinavian Sarcoma Group Register

Responsible Party: Rudiger Weiss, Clinical professor, Karolinska University Hospital
ClinicalTrials.gov Identifier: NCT01520480     History of Changes
Other Study ID Numbers: 206/02
First Posted: January 30, 2012    Key Record Dates
Last Update Posted: January 31, 2012
Last Verified: January 2012

Keywords provided by Rudiger Weiss, Karolinska University Hospital:
survival after surgery
Pathological Subtrochanteric Fractures

Additional relevant MeSH terms:
Fractures, Bone
Femoral Fractures
Hip Fractures
Wounds and Injuries
Leg Injuries
Hip Injuries