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Predictors of Postoperative Left Ventricular Function in Patients Undergoing Mitral Valve Repair for Severe Degenerative Mitral Regurgitation

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified January 2012 by University of Zurich.
Recruitment status was:  Recruiting
Valtech Cardio Ltd
Information provided by (Responsible Party):
University of Zurich Identifier:
First received: January 23, 2012
Last updated: January 25, 2012
Last verified: January 2012

The aim of the study is to investigate whether a predictive score (combination of several validated predictors) better predicts postoperative left ventricular function than any single predictor in patients undergoing mitral valve repair for degenerative mitral regurgitation.

A single center, prospective cohort study

Condition Intervention Phase
Severe Degenerative Mitral Regurgitation
Behavioral: mitral valve repair
Phase 3

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective

Further study details as provided by University of Zurich:

Estimated Enrollment: 100
Study Start Date: November 2011
Estimated Study Completion Date: May 2014
Estimated Primary Completion Date: May 2014 (Final data collection date for primary outcome measure)
Intervention Details:
    Behavioral: mitral valve repair
    Mitral valve repair in patients with degenerative mitral regurgitation

Ages Eligible for Study:   18 Years to 85 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
100 patients with mitral valve proplapse ondergoing mitral valve repair for severe mitral regurgitation

Inclusion criteria:

  • Age 18- 85 years
  • Patients with severe degenerative mitral regurgitation undergoing mitral valve repair at our institution

Exclusion criteria:

  • Functional or ischemic mitral regurgitation
  • Presence of relevant (symptomatic) Coronary Artery Disease
  • Inability of exercising on semi supine bicycle
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01519050

Contact: Ines Bühler, Study Coordinator +41 (0)44 255 11 11
Contact: Patric Biaggi, MD

University Hospital Zurich, Division of Cardiology Recruiting
Zurich, ZH, Switzerland, 8091
Sponsors and Collaborators
University of Zurich
Valtech Cardio Ltd
Principal Investigator: Patric Biaggi, MD, Senior physican University Hospital Zurich, Division of Cardiology
  More Information

Responsible Party: University of Zurich Identifier: NCT01519050     History of Changes
Other Study ID Numbers: KEK ZH 2011- 0274
Study First Received: January 23, 2012
Last Updated: January 25, 2012

Additional relevant MeSH terms:
Mitral Valve Insufficiency
Heart Valve Diseases
Heart Diseases
Cardiovascular Diseases processed this record on March 24, 2017