Predictors of Postoperative Left Ventricular Function in Patients Undergoing Mitral Valve Repair for Severe Degenerative Mitral Regurgitation

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01519050
Recruitment Status : Unknown
Verified January 2012 by University of Zurich.
Recruitment status was:  Recruiting
First Posted : January 26, 2012
Last Update Posted : January 26, 2012
Edwards Lifesciences
Information provided by (Responsible Party):
University of Zurich

Brief Summary:

The aim of the study is to investigate whether a predictive score (combination of several validated predictors) better predicts postoperative left ventricular function than any single predictor in patients undergoing mitral valve repair for degenerative mitral regurgitation.

A single center, prospective cohort study

Condition or disease Intervention/treatment
Severe Degenerative Mitral Regurgitation Behavioral: mitral valve repair

Study Type : Observational
Estimated Enrollment : 100 participants
Observational Model: Cohort
Time Perspective: Prospective
Study Start Date : November 2011
Estimated Primary Completion Date : May 2014
Estimated Study Completion Date : May 2014

Intervention Details:
  • Behavioral: mitral valve repair
    Mitral valve repair in patients with degenerative mitral regurgitation

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 85 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
100 patients with mitral valve proplapse ondergoing mitral valve repair for severe mitral regurgitation

Inclusion criteria:

  • Age 18- 85 years
  • Patients with severe degenerative mitral regurgitation undergoing mitral valve repair at our institution

Exclusion criteria:

  • Functional or ischemic mitral regurgitation
  • Presence of relevant (symptomatic) Coronary Artery Disease
  • Inability of exercising on semi supine bicycle

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01519050

Contact: Ines Bühler, Study Coordinator +41 (0)44 255 11 11
Contact: Patric Biaggi, MD

University Hospital Zurich, Division of Cardiology Recruiting
Zurich, ZH, Switzerland, 8091
Sponsors and Collaborators
University of Zurich
Edwards Lifesciences
Principal Investigator: Patric Biaggi, MD, Senior physican University Hospital Zurich, Division of Cardiology

Responsible Party: University of Zurich Identifier: NCT01519050     History of Changes
Other Study ID Numbers: KEK ZH 2011- 0274
First Posted: January 26, 2012    Key Record Dates
Last Update Posted: January 26, 2012
Last Verified: January 2012

Additional relevant MeSH terms:
Mitral Valve Insufficiency
Heart Valve Diseases
Heart Diseases
Cardiovascular Diseases