LIFE Cancer Survivorship Database for Pediatric Cancer
The purpose of this study is to develop a mechanism for utilizing the comprehensive clinical database of childhood cancer survivors at Childrens Hospital Los Angeles (CHLA) for research purposes. Using clinical information obtained from follow-up visits of childhood cancer survivors, the database will focus on interventions to improve health status and health-related quality of life in childhood cancer survivors. This study allows for establishment and analyses of a research database for LIFE survivors by the investigators listed herein. Over the last three decades, there has been marked improvement in survival following childhood cancer, with 5-year survival rates now approaching 80%. However, the use of cancer therapy at an early age can result in complications that may not be apparent until years later as the child matures. These resulting complications, called late effects, are principally related to the specific therapy employed and the age of the child at the time the therapy was administered. Late effects may affect virtually every body system and substantially impair quality of life. As many as two-thirds of childhood cancer survivors develop at least one late effect as a result of treatment, and approximately one-third have a late effect classified as severe or life threatening.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||A Research Database for Survivors of Childhood Cancer|
- create a database of Cancer Survivors [ Time Frame: Annual (up to 40 years) ] [ Designated as safety issue: No ]To use the information gained from this assessment for identification of risk factors and populations at risk, and to develop interventions to improve health status and quality of life (QOL) in childhood cancer survivors.
|Study Start Date:||February 2009|
|Estimated Study Completion Date:||December 2050|
|Estimated Primary Completion Date:||January 2050 (Final data collection date for primary outcome measure)|
Cancer Survivors of all ages (Must be diagnosed with cancer at 21 years or younger)
Eligibility Criteria: Eligibility criteria include (1) a history of cancer or similar illness diagnosed before 22 years of age; (2) cancer in remission. Methods: For subjects enrolled on this study, clinical data will be entered into the LIFE database as routinely done for all survivors, but tagged so that research analyses may be carried out and limited only to those who are enrolled on this study.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01518400
|Contact: Diana Palmafirstname.lastname@example.org|
|United States, California|
|Children's Hospital Los Angeles||Recruiting|
|Los Angeles, California, United States, 90027|
|Contact: Diana Palma 323-361-5973 email@example.com|
|Principal Investigator: David Freyer, DO, MS|
|Principal Investigator:||David Freyer, DO||Children's Hospital Los Angeles|