Incidence and Predictive Factors of Intestinal Injury in Patients Undergoing Heart Valve Replacements
Recruitment status was Recruiting
The purpose of this study is to investigate the incidence and predictive factors related to intestinal injury in patients undergoing heart valve replacement through a multicenter study in China.
Injury of Other and Multiple Parts of Small Intestine
|Study Design:||Time Perspective: Prospective|
|Official Title:||Official Title is Required by the WHO and ICMJE|
- score of gut dysfunction [ Time Frame: eight months ] [ Designated as safety issue: No ]At different time points, gut dysfunction is graded according to previous criterion.
- The duration of cardiopulmonary bypass [ Time Frame: Eight months ] [ Designated as safety issue: No ]Record the duration of cardiopulmonary bypass
- The duration for aortic artery clamping [ Time Frame: eight months ] [ Designated as safety issue: No ]
Biospecimen Retention: Samples With DNA
Blood samples are retained for the detections of some biomarkers and gene polymorphism.
|Study Start Date:||October 2011|
|Estimated Study Completion Date:||November 2012|
|Estimated Primary Completion Date:||October 2012 (Final data collection date for primary outcome measure)|
|patients with cardiac surgery|
Intestinal injury is one of main reasons for mobidity and mortality after heart valve replacement, but its incidence and potential risk factors remain unclear. A multicenter study in China is undertaken to investigate the incidence and predictive factors related to intestinal injury in patients undergoing heart valve replacement.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01516359
|Contact: Ke Xuan Liu, MD,Ph.D.||86-20-87755766 ext firstname.lastname@example.org|
|Department of Anesthesiology, The First Affiliated Hospital, Sun Yat-sen University||Recruiting|
|Guangzhou, Guangdong, China, 510080|
|Contact: Ke Xuan Liu, MD, Ph.D. 86-13710684096 email@example.com|
|Contact: Cai Li, MD 86-18602017796 firstname.lastname@example.org|
|Principal Investigator: Ke Xuan Liu, MD, Ph.D.|
|Principal Investigator:||Ke Xuan Liu, MD, Ph.D||First Affiliated Hospital, Sun Yat-Sen University|