LOXL1 Polymorphism in Pseudoexfoliation Syndrome
Recruitment status was: Recruiting
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||Evaluation of LOXL1 Polymorphism in Pseudoexfoliation Syndrome in the Korean Population|
- Genotypes of the three single nucleotide polymorphisms of LOXL1 (rs1048661, rs3825942, rs2165241) [ Time Frame: about 1 year (when all patients were recruited) ]Genotypes of the three single nucleotide polymorphisms of LOXL1 were analyzed by direct sequencing, after obtained from the peripheral blood sampling from patients.
Biospecimen Retention: Samples With DNA
|Study Start Date:||December 2011|
|Estimated Study Completion Date:||December 2012|
|Estimated Primary Completion Date:||December 2012 (Final data collection date for primary outcome measure)|
The study group composted of the patients with pseudoexfoliation syndrome
To evaluate the association profiles of the lysyl oxidase-like 1 gene polymorphisms with pseudoexfoliation syndrome in the Korean population, peripheral blood sampling will be done from the patients with pseudoexfoliation.
And genotypes of the three single nucleotide polymorphisms of lysyl oxidase-like 1 gene , rs1048661, rs3825942, rs2165241 were analyzed by direct sequencing.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01515735
|Korea, Republic of|
|Samsung medical center|
|Seoul, Korea, Republic of, 135710|
|Study Chair:||Changwon Kee, M.D., PhD||Samsung Medical Center|