Analyzing the Composition of Tears and Blood for Discovery of Novel Signatures of Aggressive Prostate Cancer
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The purpose of this research study is to compare profiles in the blood and tears of patients with and without prostate cancer with the goal of developing a method of separating men with aggressive and non-aggressive disease.
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Ages Eligible for Study:
35 Years to 80 Years (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Participants will be selected from those outpatients followed in the Winthrop P. Rockefeller Cancer Institute (located at the University of Arkansas for Medical Sciences).
Male, 35-80 years old
Patients who present for a routine check-up
Patients who present for the evaluation of an abnormal exam or test (elevated PSA, abnormal DRE, etc.)
Patients who present for the evaluation of a palpable nodule or induration on prostate exam
Patients may present with a biopsy proven prostate cancer from outside physician for inclusion into arms 2 or 3
For group 1 a negative prostate biopsy
Patient < 35 or > 81 years of age
Concurrent eye infection or trauma
Abnormal production of tears (too much or too little)
Any other conditions the PI or staff feels will not fulfill the criteria for study entry or will place the subject in a harmful environment