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Correlation of PaCO2 to the Inspired and Expired Oxygen Gradient (O2 Fraction)

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ClinicalTrials.gov Identifier: NCT01513213
Recruitment Status : Completed
First Posted : January 20, 2012
Last Update Posted : January 24, 2017
Sponsor:
Information provided by (Responsible Party):

Study Description
Brief Summary:
The purpose of this study is to evaluate whether a correlation exists between the partial pressure of carbon dioxide existing within arterial blood and the gradient between inhaled and exhaled fractions of oxygen.

Condition or disease
Neurosurgery

Study Design

Study Type : Observational
Actual Enrollment : 65 participants
Observational Model: Case-Only
Time Perspective: Cross-Sectional
Official Title: Correlation of PaCO2 to the Inspired and Expired Oxygen Gradient
Study Start Date : October 2011
Primary Completion Date : May 2014
Study Completion Date : December 2016

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Oxygen Therapy
U.S. FDA Resources

Groups and Cohorts


Outcome Measures

Primary Outcome Measures :
  1. Correlate the level of carbon dioxide within arterial blood to inspired and expired oxygen gradient. [ Time Frame: At least 2 hours ]
    Compare the levels of carbon dioxide found in the patient's blood to the amounts of carbon dioxide and oxygen in the air that the patient inhales and exhales. If a relationship exists between the levels of carbon dioxide in the blood and the levels of carbon dioxide and oxygen inhaled and exhaled by the patient, anesthesiologists will be able to use this relationship to adjust ventilators during anesthesia without having to take blood from an artery.


Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 65 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Adults age 18 to 65 scheduled for a surgical procedure that will last at least two hours and for whom arterial cannulation and at least two arterial blood gas analyses are planned during the surgery.
Criteria

Inclusion Criteria:

  • Age 18 to 65.
  • Scheduled for surgical procedure that will last at least 2 hours.
  • Arterial cannulation is planned because of either the complexity of the surgery or patient comorbidity.
  • At least two arterial blood gas analyses are planned during the surgery.

Exclusion Criteria:

  • No arterial cannulation is necessary or planned for the procedure.
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01513213


Locations
United States, Washington
Swedish Medical Center
Seattle, Washington, United States, 98122
Sponsors and Collaborators
Swedish Medical Center
Investigators
Principal Investigator: Arthur M Lam, MD, FRCPC Swedish Medical Center
More Information

Responsible Party: Swedish Medical Center
ClinicalTrials.gov Identifier: NCT01513213     History of Changes
Other Study ID Numbers: 5119S-11
First Posted: January 20, 2012    Key Record Dates
Last Update Posted: January 24, 2017
Last Verified: January 2017

Keywords provided by Swedish Medical Center:
Arterial cannulation
Blood gas
Carbon dioxide
Arterial blood
Oxygen
Oxygen fractions