Try our beta test site
IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more...

Assessing Perceived Versus Actual Knowledge and Quality of Life in Pre-Dialysis Chronic Kidney Disease (CKD) Patients

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified April 2015 by National University, Singapore.
Recruitment status was:  Recruiting
Information provided by (Responsible Party):
Priscilla How, Pharm.D., BCPS, National University, Singapore Identifier:
First received: January 6, 2012
Last updated: April 14, 2015
Last verified: April 2015

Aims: The investigators' primary objective is to assess both perceived and actual disease knowledge in local pre-dialysis Chronic Kidney Disease (CKD) patients. The investigators hypothesize that actual disease knowledge is poorer than perceived. As the secondary objectives, the investigators will also assess the HRQoL and examine the association between level of knowledge and HRQoL in pre-dialysis CKD patients. The investigators hypothesize that HRQoL of pre-dialysis CKD patients is poorer than that of the general population while pre-dialysis CKD patients with greater disease knowledge have a better HRQoL than those with poorer knowledge.

Methodology: A survey was developed to assess both perceived and actual knowledge on five aspects - general knowledge, nephrotoxic medications, diet restrictions, symptoms of CKD and its complications and renal replacement therapy (RRT) options. For the assessment of HRQoL, the following questionnaires will be used - Kidney Disease Quality of Life-Short Form (KDQOL-SF) version 1.3, EuroQoL 5 Dimensions (EQ-5D), Family Functioning Measure (FFM), and Oslo-3 Social Support Scale (OSS-3). All study questionnaires will be provided in 3 main languages - English, Chinese and Malay. A standardized data collection form was developed to retrospectively collect demographic and clinical information from the patients' electronic medical records and patient charts. Descriptive statistics will be used to report all results.

Chronic Kidney Disease Stage 3
Chronic Kidney Disease Stage 4
Chronic Kidney Disease Stage 5

Study Type: Observational
Study Design: Time Perspective: Cross-Sectional
Official Title: Assessing Perceived Versus Actual Knowledge and Quality of Life in Pre-Dialysis CKD Patients

Resource links provided by NLM:

Further study details as provided by National University, Singapore:

Estimated Enrollment: 400

Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Predialysis patients with stage 3-5 chronic kidney disease patients seen in outpatient renal clinic in National University Hospital, Singapore

Inclusion Criteria:

  • patients at least 21 years of age,
  • able to read English, Chinese or Malay,
  • have stage 3 to 5 CKD as identified from their medical records, but are not receiving dialysis.

Exclusion Criteria:

  • patients who do not consent,
  • have already been started on dialysis,
  • are cognitively impaired as assessed by the recruiter or unable to fill up questionnaires on their own.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01509716

Contact: Priscilla P How, Pharm.D. (65) 6516 4906

National University Hospital Recruiting
Singapore, Singapore
Contact: Priscilla P How, Pharm.D.    (65) 6516 4906   
Principal Investigator: Priscilla P How, Pharm.D.         
Sponsors and Collaborators
National University, Singapore
  More Information

Responsible Party: Priscilla How, Pharm.D., BCPS, Assistant Professor, National University, Singapore Identifier: NCT01509716     History of Changes
Other Study ID Numbers: DSRB Domain E/2011/02008
Study First Received: January 6, 2012
Last Updated: April 14, 2015

Keywords provided by National University, Singapore:

Additional relevant MeSH terms:
Renal Insufficiency, Chronic
Kidney Diseases
Renal Insufficiency
Urologic Diseases processed this record on May 25, 2017