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Assessing Perceived Versus Actual Knowledge and Quality of Life in Pre-Dialysis Chronic Kidney Disease (CKD) Patients

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ClinicalTrials.gov Identifier: NCT01509716
Recruitment Status : Unknown
Verified April 2015 by Priscilla How, Pharm.D., BCPS, National University, Singapore.
Recruitment status was:  Recruiting
First Posted : January 13, 2012
Last Update Posted : April 15, 2015
Sponsor:
Information provided by (Responsible Party):
Priscilla How, Pharm.D., BCPS, National University, Singapore

Study Description
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Brief Summary:

Aims: The investigators' primary objective is to assess both perceived and actual disease knowledge in local pre-dialysis Chronic Kidney Disease (CKD) patients. The investigators hypothesize that actual disease knowledge is poorer than perceived. As the secondary objectives, the investigators will also assess the HRQoL and examine the association between level of knowledge and HRQoL in pre-dialysis CKD patients. The investigators hypothesize that HRQoL of pre-dialysis CKD patients is poorer than that of the general population while pre-dialysis CKD patients with greater disease knowledge have a better HRQoL than those with poorer knowledge.

Methodology: A survey was developed to assess both perceived and actual knowledge on five aspects - general knowledge, nephrotoxic medications, diet restrictions, symptoms of CKD and its complications and renal replacement therapy (RRT) options. For the assessment of HRQoL, the following questionnaires will be used - Kidney Disease Quality of Life-Short Form (KDQOL-SF) version 1.3, EuroQoL 5 Dimensions (EQ-5D), Family Functioning Measure (FFM), and Oslo-3 Social Support Scale (OSS-3). All study questionnaires will be provided in 3 main languages - English, Chinese and Malay. A standardized data collection form was developed to retrospectively collect demographic and clinical information from the patients' electronic medical records and patient charts. Descriptive statistics will be used to report all results.


Condition or disease
Chronic Kidney Disease Stage 3 Chronic Kidney Disease Stage 4 Chronic Kidney Disease Stage 5

Study Design
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Study Type : Observational
Estimated Enrollment : 400 participants
Time Perspective: Cross-Sectional
Official Title: Assessing Perceived Versus Actual Knowledge and Quality of Life in Pre-Dialysis CKD Patients

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Kidney Diseases
U.S. FDA Resources

Groups and Cohorts
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Outcome Measures
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Eligibility Criteria
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Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Predialysis patients with stage 3-5 chronic kidney disease patients seen in outpatient renal clinic in National University Hospital, Singapore
Criteria

Inclusion Criteria:

  • patients at least 21 years of age,
  • able to read English, Chinese or Malay,
  • have stage 3 to 5 CKD as identified from their medical records, but are not receiving dialysis.

Exclusion Criteria:

  • patients who do not consent,
  • have already been started on dialysis,
  • are cognitively impaired as assessed by the recruiter or unable to fill up questionnaires on their own.
Contacts and Locations
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Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01509716


Contacts
Contact: Priscilla P How, Pharm.D. (65) 6516 4906 priscillahow@nus.edu.sg

Locations
Singapore
National University Hospital Recruiting
Singapore, Singapore
Contact: Priscilla P How, Pharm.D.    (65) 6516 4906    priscillahow@nus.edu.sg   
Principal Investigator: Priscilla P How, Pharm.D.         
Sponsors and Collaborators
National University, Singapore
More Information
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Study Description Study Design Groups and Cohorts Outcome Measures Eligibility Criteria Contacts and Locations More Information

Responsible Party: Priscilla How, Pharm.D., BCPS, Assistant Professor, National University, Singapore
ClinicalTrials.gov Identifier: NCT01509716     History of Changes
Other Study ID Numbers: DSRB Domain E/2011/02008
First Posted: January 13, 2012    Key Record Dates
Last Update Posted: April 15, 2015
Last Verified: April 2015

Keywords provided by Priscilla How, Pharm.D., BCPS, National University, Singapore:
Predialysis

Additional relevant MeSH terms:
Kidney Diseases
Renal Insufficiency, Chronic
Kidney Failure, Chronic
Urologic Diseases
Renal Insufficiency