Assessment of Zinc Absorption From a Phytic Acid Rich Complementary Food
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ClinicalTrials.gov Identifier: NCT01506648
Recruitment Status :
First Posted : January 10, 2012
Last Update Posted : November 28, 2016
Swiss Federal Institute of Technology
Information provided by (Responsible Party):
Prof. Michael B. Zimmermann, Swiss Federal Institute of Technology
Fractional absorption of zinc [ Time Frame: 33 days ]
Fractional absorption of zinc is estimated by using the double isotope tracer ratio technique by administering 67Zn as oral and 70Zn as intravenous stable isotopes.The urinary enrichment with both isotopes is measured in a spot urine sample by inductively coupled plasma mass spectrometry.
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Ages Eligible for Study:
12 Months to 24 Months (Child)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Study not related to a disease. Nutrition study without drug drug administration. Assessment of zinc absorption from a phytic acid rich complementary food, consumed by young children immediately after the addition of the enzyme phytase. A randomized single blind study
12-24 month old
Male of female
Height and weight between -2.0 SD and +2.0 SD with respect to WHO child growth standards.
No mineral and vitamin supplements 2 weeks prior to the study and during the whole duration of the study
Body temperature ≥ 37.5°C
Hemoglobin ≤ 7g/dL
Positive RDT test
Any metabolic, gastrointestinal or chronic disease (according to the statement of the subject's parent) known chronic diseases at the gastrointestinal tract)
Long term mediation (that may affect zinc metabolism) during the whole study to interact with zinc metabolism (such as kidney diseases or