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Multi-joint Coordination Underlies Upright Balance Control in Elderly With Osteoporosis

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ClinicalTrials.gov Identifier: NCT01504230
Recruitment Status : Completed
First Posted : January 5, 2012
Last Update Posted : December 16, 2016
Sponsor:
Information provided by (Responsible Party):
National Taiwan University Hospital

Brief Summary:
Osteoporosis is a prevalent health concern among older adults and is associated with an increased risk of falls that can cause fracture, injury and even mortality. Identifying the factors related to falls occur within this population is essential for the development of effective regimes for fall prevention. The long-term objectives of this work are to ascertain the mechanisms for effectively controlling balance in seniors with osteoporosis and to provide a basis for developing fall prevention programs. The entire body's center of mass (CoM) is a critical indicator for balance control and the coordination among joints and muscles to control the CoM is still unclear. The aim1 of this study is to develop biomechanical models that control the entire body's center of mass (CoM) during upright quiet stance in seniors with osteoporosis. The aim2 of this study is to identify the mechanism to control the entire body's CoM after receiving a balance perturbation in seniors with osteoporosis. The findings of this research can provide needed information regarding the processes of balance control in this vulnerable osteoporosis population, and has the potential to be applied to individuals with other neuromuscular and orthopedic deficits.

Condition or disease
Osteoporosis

Study Type : Observational
Actual Enrollment : 50 participants
Observational Model: Cohort
Time Perspective: Cross-Sectional
Official Title: Multi-joint Coordination Underlies Upright Balance Control in Elderly With Osteoporosis
Study Start Date : September 2011
Actual Primary Completion Date : July 2013
Actual Study Completion Date : July 2013

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Osteoporosis

Group/Cohort
health older adults
Osteoporosis participants




Information from the National Library of Medicine

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Ages Eligible for Study:   65 Years to 85 Years   (Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
community sample
Criteria

Inclusion Criteria:

  • for healthy older adults (OA)

    1. can stand for 5 minutes and walk for 6 minutes independently
    2. normal or corrected to normal vision
    3. an age between 65-85 years
    4. no osteoporosis (T-score above -2.5)
  • for osteoporosis participants (OP)

    1. can stand for 5 minutes and walk for 6 minutes independently
    2. normal or corrected to normal vision
    3. an age between 65-85 years
    4. no osteoporosis (T-score below -2.5)

Exclusion Criteria:

  1. pregnant women
  2. cancer diagnosis
  3. sensory-motor deficits
  4. the BMI is larger than 30 or smaller than 18

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01504230


Locations
Taiwan
School & Graduate Institute of Physical Therapy College of Medicine, National Taiwan University
Taipei, Taiwan
Sponsors and Collaborators
National Taiwan University Hospital
Investigators
Principal Investigator: Wei-Li Hsu, PhD National Taiwan University Hospital

Responsible Party: National Taiwan University Hospital
ClinicalTrials.gov Identifier: NCT01504230     History of Changes
Other Study ID Numbers: 201104056RB
First Posted: January 5, 2012    Key Record Dates
Last Update Posted: December 16, 2016
Last Verified: December 2016

Keywords provided by National Taiwan University Hospital:
To ascertain the mechanisms for effectively controlling balance in seniors with osteoporosis and to provide a basis for developing fall prevention programs.
To develop biomechanical models that control the entire body's center of mass (CoM) during upright quiet stance in seniors with osteoporosis.
To identify the mechanism to control the entire body's CoM after receiving a balance perturbation in seniors with osteoporosis.

Additional relevant MeSH terms:
Osteoporosis
Bone Diseases, Metabolic
Bone Diseases
Musculoskeletal Diseases
Metabolic Diseases