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Drinking Habits of Glaucoma Patients and Age Matched Controls

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ClinicalTrials.gov Identifier: NCT01503996
Recruitment Status : Completed
First Posted : January 4, 2012
Last Update Posted : November 30, 2015
Sponsor:
Information provided by (Responsible Party):
Dr. Karin Pillunat, Technische Universität Dresden

Brief Summary:
The purpose of this study is to examine if a chronic dehydration is a risk factor for the developement or progression of some forms of glaucoma.

Condition or disease Intervention/treatment
Dehydration Glaucoma Behavioral: alter drinking habits

Detailed Description:

Glaucoma patients who are hospitalized for diurnal intraocular pressure measurements and glaucoma assessment are asked about their drinking habits. Objective evaluation of hydration status is assessed with the Body Composition Monitor (Fresenius). Retinal Vessel Analysis and Laser Doppler Flowmetry are investigated in subgroups.

The control group are also hospitalized patients who do not suffer from glaucoma.


Study Type : Observational
Actual Enrollment : 600 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Clinical Study to Evaluate the Drinking Habits of Glaucoma Patients and Age Matched Controls
Study Start Date : October 2011
Primary Completion Date : October 2015
Study Completion Date : October 2015

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Dehydration Glaucoma
U.S. FDA Resources

Group/Cohort Intervention/treatment
glaucoma
hospitalized glaucoma patients
Behavioral: alter drinking habits
if dehydration is apparent, more fluid intake is recommended
controls
hospitalized patients without glaucoma
Behavioral: alter drinking habits
if dehydration is apparent, more fluid intake is recommended



Primary Outcome Measures :
  1. Dehydration [ Time Frame: 4 years ]
    The composition of a patient's body, in particular a patient's water content are determined with bioimpedance spectroscopy (Body Composition Monitor, FRESENIUS)


Secondary Outcome Measures :
  1. microvascular changes [ Time Frame: 4 years ]
    To investigate differences in retinal vessel diameters measured with the Retinal Vessel Analyzer (RVA, IMEDOS) in glaucoma patients and controls



Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Glaucoma patients who are hospitalized for diurnal intraocular pressure measurements and glaucoma assessment.

Controls who are hospitalizes because of an other ophthalmic disease and do not suffer from glaucoma.

Criteria

Inclusion Criteria:

  • glaucoma patients
  • controls

Exclusion Criteria:

  • psychiatric disease,
  • epilepsy, pregnancy,
  • nutritional disorder,
  • malfunction of blood clotting and wound healing,
  • pacemaker,
  • metallic stents

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01503996


Locations
Germany
University Eye Clinic Dresden
Dresden, Germany, 01307
Sponsors and Collaborators
Technische Universität Dresden
Investigators
Principal Investigator: Karin R Pillunat, MD University Eye Clinic Dresden

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Dr. Karin Pillunat, Dr. med., Technische Universität Dresden
ClinicalTrials.gov Identifier: NCT01503996     History of Changes
Other Study ID Numbers: Drinking/Glaucoma
First Posted: January 4, 2012    Key Record Dates
Last Update Posted: November 30, 2015
Last Verified: November 2015

Keywords provided by Dr. Karin Pillunat, Technische Universität Dresden:
dehydration
risk factor
glaucoma
Controls

Additional relevant MeSH terms:
Glaucoma
Dehydration
Ocular Hypertension
Eye Diseases
Water-Electrolyte Imbalance
Metabolic Diseases
Pathologic Processes