DaHuang GangTsao Tang to Improve the Appetite Loss Condition of Cancer Patients (TCM)
Recruitment status was Recruiting
Appetite loss is a severe and common symptom among late-stage cancer patients, and it causes great the anxiety for the patient's family. In TCM theory, the investigators call these patients are in block and repulsion condition. The investigators try to set a study to use the herbal medicine solution taken in frequent small amounts by cancer patients in late-stage to improve the appetite loss condition. Through this method, the investigators not only want to improve the quality of life of cancer patients in late-stage but also set a valuable treatment.
|Study Design:||Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Single Blind (Subject)
Primary Purpose: Supportive Care
|Official Title:||Taking Herbal Formula：DaHuang GangTsao Tang to Improve the Appetite Loss Condition of Cancer Patients in Late-stage：A Clinical Control Trial Study|
- appetite score [ Time Frame: 6 days ] [ Designated as safety issue: Yes ]The investigators detect the patients' appetite condition at the 1st,3rd and 6th day.
|Study Start Date:||March 2011|
|Estimated Study Completion Date:||March 2012|
|Primary Completion Date:||September 2011 (Final data collection date for primary outcome measure)|
Active Comparator: herbal medicine
Drug: DaHuang GanTsao Tang
Other Name: Herbal Medicine Group
- 1. 2 grams of DaHuang abstract powder and 0.5 grams GanTsao abstract powder are mixed and separated into four packages;
- 2. each package was given to each patient four times a day (three time after meal and one time before sleep);
- 3. each patient received the usual medication of the hospice ward at the same time;
- 4. record the patients' score of pre-test, mid-test and after-test of QIPCTP at the 1st day, the 3rd day and the 6th day;
- 5. record the patients' score of EORTC QLQ-C30 V3.0 and ECOG (Eastern Cooperative Oncology Group Performance Status) at the 1st day and the 6th day.
- 1. each patient received the usual medication of the hospice ward during the trial interval;
- 2. record the patients' score of receive pre-test, mid-test and after-test of QIPCTP at the 1st day, the 3rd day and the 6th day;
- 3. record the patients' score of EORTC QLQ-C30 V3.0 and ECOG (Eastern Cooperative Oncology Group Performance Status) at at the 1st day and the 6th day.
Medicine DaHuang herbal abstract powder is produced by Sun Ten Pharmaceutical Co., Ltd, and it's product serial number: 276001. GanCao herbal abstract powder is also produced by Sun Ten Pharmaceutical Co., Ltd, and it's product serial number: 185645. Each herbal abstract powder is qualified with the data of HPLC to confirm each content and stability. The pharmaceutical company is qualified by Good Manufacturing Practice (GMP) certification in Taiwan.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01503346
|Contact: Y D LIU, Masterfirstname.lastname@example.org|
|Contact: S C YANG, Masteremail@example.com|
|Changhua Christan Hospital||Recruiting|
|Changhua City, Changhua Country, Taiwan, 500|
|Contact: Y D LIU, Master 886-988-285196 firstname.lastname@example.org|
|Contact: S C YANG, Master 886-937-251181 email@example.com|
|Study Chair:||Yu De LIU, Master||Changhua Christian Hospital|