Finding Atrial Fibrillation in Patients With Unexplained Stroke Using Longterm Cardiac Monitoring (SURPRISE)

This study is ongoing, but not recruiting participants.
Information provided by (Responsible Party):
Hanne Christensen, Bispebjerg Hospital Identifier:
First received: December 21, 2011
Last updated: July 15, 2014
Last verified: July 2014
The SURPRISE study investigates atrial fibrillation(AFIB) in patients with a previous unexplained stroke. It uses long term monitoring of the heart of up to three years, searching for paroxysmal atrial fibrillation(PAF) otherwise undetected in this population.


Study Type: Observational
Study Design: Time Perspective: Prospective
Official Title: Stroke Prior to Diagnosis of Atrial Fibrillation Using Longterm Observation With Implantable Cardiac Monitoring Apparatus Reveal(SURPRISE) -the SURPRISE Study

Resource links provided by NLM:

Further study details as provided by Bispebjerg Hospital:

Estimated Enrollment: 100
Study Start Date: April 2010
Estimated Study Completion Date: October 2014
Primary Completion Date: October 2013 (Final data collection date for primary outcome measure)
Detailed Description:

The SURPRISE study investigates the patients with cryptogenic stroke or transient ischemic attack (TIA), monitoring them with a cardiac loop recorder for up to three years.

it aims at estimating the amount of paroxysmal atrial fibrillation within our population of cryptogenic stroke patients.

Standard workup for a stroke patient does offer cardiac evaluation, but monitoring is limited to the time admitted, often just a few days.


Ages Eligible for Study:   18 Months and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
the patients are included from the investigators stroke unit and day clinic

Inclusion Criteria:

  • Computerized Tomography (CT) or Magnetic resonance imaging (MRI) verified cryptogenic stroke or TIA;
  • > 18 years of age,
  • the ability to provide a written consent

Exclusion Criteria:

  • prior or known AFIB
  • AF found during work up including 24 hour telemetric monitoring.
  Contacts and Locations
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Please refer to this study by its identifier: NCT01498146

Bispebjerg Hospital, University Hospital of Copenhagen, dept of Neurology
Copenhagen, Denmark, DK-2400
Sponsors and Collaborators
Bispebjerg Hospital
Principal Investigator: Hanne Christensen, MD, PhD, DMSci University of Copenhagen
  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Hanne Christensen, Associate Research Professor, Consultant neurologist, Bispebjerg Hospital Identifier: NCT01498146     History of Changes
Other Study ID Numbers: H-4-2010-014 
Study First Received: December 21, 2011
Last Updated: July 15, 2014
Health Authority: Denmark: National Board of Health
Denmark: Danish Dataprotection Agency
Denmark: Ethics Committee

Keywords provided by Bispebjerg Hospital:
cryptogenic stroke
atrial fibrillation
longterm monitoring
loop recorder

Additional relevant MeSH terms:
Atrial Fibrillation
Arrhythmias, Cardiac
Brain Diseases
Cardiovascular Diseases
Central Nervous System Diseases
Cerebrovascular Disorders
Heart Diseases
Nervous System Diseases
Pathologic Processes
Vascular Diseases processed this record on May 24, 2016