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identification of factors predisposing for Post-Infectious Irritable Bowel Syndrome (PI-IBS) development after an episode of traveler's diarrhea
identification of systemic (serum) and local (biopsy) changes in infectious and immunological activity during infection and correlation with Irritable Bowel Syndrome (IBS) symptoms, persisting after traveler's diarrhea
4 study visits: before traveling, 2 weeks after traveling, 6 months after traveling, 12 months after traveling
at each study visit following investigations: blood collection, stool collection, questionnaires, rectal biopsy
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Ages Eligible for Study:
18 Years to 70 Years (Adult, Senior)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Travelers to tropical destinations visiting the outpatient clinic for vaccinations in a tertiary care hospital.
traveling to South-America, Africa, South-East Asia
traveling for 1-10 weeks
use of antibiotics/corticosteroids 2 weeks before travelling