Study With Idebenone in Patients With Chronic Vision Loss Due to Leber's Hereditary Optic Neuropathy (LHON)
This study has been withdrawn prior to enrollment.
First Posted: December 20, 2011
Last Update Posted: August 22, 2014
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Information provided by (Responsible Party):
The objective of the study is to determine whether administration of idebenone can shorten the time to improvement of visual acuity in patients with chronic vision loss due to LHON.
Leber's Hereditary Optic Neuropathy
Placebo Comparator: Placebo
Information from the National Library of Medicine
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|Ages Eligible for Study:
||10 Years to 65 Years (Child, Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
- Age > or equal 10 years and < 65 years
- Impaired visual acuity in affected eyes due to LHON: Visual acuity in best eye >0.4 logMAR
- No explanation for visual loss besides LHON
- Any previous use of idebenone
- Participation in another clinical trial of any investigational drug within 3 months prior to Baseline
- Previous participation in Study SNT-II-003 (RHODOS) for idebenone.
No Contacts or Locations Provided
History of Changes
|Other Study ID Numbers:
||December 16, 2011
||December 20, 2011
|Last Update Posted:
||August 22, 2014
Additional relevant MeSH terms:
Optic Atrophy, Hereditary, Leber
Optic Atrophies, Hereditary
Eye Diseases, Hereditary
Optic Nerve Diseases
Cranial Nerve Diseases
Nervous System Diseases
Heredodegenerative Disorders, Nervous System
Genetic Diseases, Inborn
Molecular Mechanisms of Pharmacological Action
Physiological Effects of Drugs