Study With Idebenone in Patients With Chronic Vision Loss Due to Leber's Hereditary Optic Neuropathy (LHON)
This study has been withdrawn prior to enrollment.
First Posted: December 20, 2011
Last Update Posted: August 22, 2014
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government.
Read our disclaimer for details.
Information provided by (Responsible Party):
The objective of the study is to determine whether administration of idebenone can shorten the time to improvement of visual acuity in patients with chronic vision loss due to LHON.
Leber's Hereditary Optic Neuropathy
Placebo Comparator: Placebo
Information from the National Library of Medicine
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
||10 Years to 65 Years (Child, Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
- Age > or equal 10 years and < 65 years
- Impaired visual acuity in affected eyes due to LHON: Visual acuity in best eye >0.4 logMAR
- No explanation for visual loss besides LHON
- Any previous use of idebenone
- Participation in another clinical trial of any investigational drug within 3 months prior to Baseline
- Previous participation in Study SNT-II-003 (RHODOS) for idebenone.
No Contacts or Locations Provided
History of Changes
|Other Study ID Numbers:
||December 16, 2011
||December 20, 2011
|Last Update Posted:
||August 22, 2014
Additional relevant MeSH terms:
Optic Nerve Diseases
Optic Atrophy, Hereditary, Leber
Cranial Nerve Diseases
Nervous System Diseases
Optic Atrophies, Hereditary
Heredodegenerative Disorders, Nervous System
Eye Diseases, Hereditary
Genetic Diseases, Inborn
Molecular Mechanisms of Pharmacological Action
Physiological Effects of Drugs