Management of Acute Myocardial Infarction in the Presence of Left Bundle Branch Block
|ClinicalTrials.gov Identifier: NCT01494870|
Recruitment Status : Unknown
Verified January 2012 by Ass.Prof. Dmitry Duplyakov M.D., Ph.D., Samara Regional Cardiology Dispensary.
Recruitment status was: Not yet recruiting
First Posted : December 19, 2011
Last Update Posted : January 10, 2012
|Condition or disease||Intervention/treatment||Phase|
|Acute Coronary Syndrome||Procedure: PCI||Not Applicable|
Current recommendations on the treatment of acute coronary syndrome (ACS) dictate urgent reperfusion therapy in the case of evolving myocardial infarction with ST-segment elevation (STEMI). Optimal use of PCI (preferably) or thrombolysis in this situation requires a rapid and correct diagnosis.
According to the ESC'2008 and ACC/AHA'2009 focused update guidelines patients admitted to the hospital within 12 hours after the onset of chest pain with new (or presumably new) left bundle-branch block (LBBB) should be treated like patients having STEMI (class I, level A). However, it is well-known that in patients with concomitant LBBB, the ECG manifestations of acute myocardial injury may be masked.
ACS may occur in a patient with "true old" LBBB (when doctor has/has not an ability to compare the new ECG with the previous one) or (presumably) new LBBB.
There is a high risk of non receiving appropriate therapy or of receiving inappropriate therapy (thrombolysis instead of LMWH/UFH/fondaparinux).
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||300 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Study Start Date :||January 2012|
|Estimated Primary Completion Date :||June 2013|
|Estimated Study Completion Date :||November 2013|
- mortality [ Time Frame: 30 days ]
- Number of participants survived [ Time Frame: 1 year ]
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01494870
|Contact: Dmitry Duplyakov, MD, PhDemail@example.com|
|Contact: Igor Yavelov, MD, PhDfirstname.lastname@example.org|
|Samara Regional Cardiology Dispansery||Not yet recruiting|
|Samara, Russian Federation, 443070|
|Principal Investigator: Dmitry Duplyakov, MD, PhD|