Management of Acute Myocardial Infarction in the Presence of Left Bundle Branch Block
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|ClinicalTrials.gov Identifier: NCT01494870|
Recruitment Status : Unknown
Verified January 2012 by Ass.Prof. Dmitry Duplyakov M.D., Ph.D., Samara Regional Cardiology Dispensary.
Recruitment status was: Not yet recruiting
First Posted : December 19, 2011
Last Update Posted : January 10, 2012
|Condition or disease||Intervention/treatment||Phase|
|Acute Coronary Syndrome||Procedure: PCI||Not Applicable|
Current recommendations on the treatment of acute coronary syndrome (ACS) dictate urgent reperfusion therapy in the case of evolving myocardial infarction with ST-segment elevation (STEMI). Optimal use of PCI (preferably) or thrombolysis in this situation requires a rapid and correct diagnosis.
According to the ESC'2008 and ACC/AHA'2009 focused update guidelines patients admitted to the hospital within 12 hours after the onset of chest pain with new (or presumably new) left bundle-branch block (LBBB) should be treated like patients having STEMI (class I, level A). However, it is well-known that in patients with concomitant LBBB, the ECG manifestations of acute myocardial injury may be masked.
ACS may occur in a patient with "true old" LBBB (when doctor has/has not an ability to compare the new ECG with the previous one) or (presumably) new LBBB.
There is a high risk of non receiving appropriate therapy or of receiving inappropriate therapy (thrombolysis instead of LMWH/UFH/fondaparinux).
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||300 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Study Start Date :||January 2012|
|Estimated Primary Completion Date :||June 2013|
|Estimated Study Completion Date :||November 2013|
- Procedure: PCI
urgent PCI on admission
- mortality [ Time Frame: 30 days ]
- Number of participants survived [ Time Frame: 1 year ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01494870
|Contact: Dmitry Duplyakov, MD, PhDemail@example.com|
|Contact: Igor Yavelov, MD, PhDfirstname.lastname@example.org|
|Samara Regional Cardiology Dispansery||Not yet recruiting|
|Samara, Russian Federation, 443070|
|Principal Investigator: Dmitry Duplyakov, MD, PhD|