The Effect of Marketing Variable on Effect of Active Drugs
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|ClinicalTrials.gov Identifier: NCT01493908|
Recruitment Status : Unknown
Verified December 2011 by Hadassah Medical Organization.
Recruitment status was: Not yet recruiting
First Posted : December 16, 2011
Last Update Posted : December 16, 2011
The efficacy of the placebo effect has been proved in many prior studies by comparing the symptoms and measures of patients. Placebo has been proved to help in treating illnesses such as depression, stomach ulcer and chronic headaches.
A Meta analysis checked 47 studies about placebo and showed great significance when a patient is treated with placebo pill, no active substance, just by activating conditioning and expectation mechanism in his body, thus providing to the healing process, and that is it's importance.
In recent years studies established a relationship between marketing variables (such as price, label) to the efficacy of a product. In addition- a unique research run in 2008 showed a significant relationship between the marketing strategies and the efficacy of medication; more specifically, patients in this research experienced less (controlled) pain when treated with placebo medication introduced to them as more expensive than patients treated with placebo medication that was introduced to them as much cheaper. All patients were treated with the exact same medication.
In the investigator's experiment the investigators design a laboratory experiment to determine if marketing factors could invoke the placebo effects described earlier. For the initial laboratory experiment, we decided to examine the difference in price, on the efficacy of an OTC analgesic through the mediation of low- voltage electrical pulses to the patient's wrist.
The investigators study hypothesis is that marketing variables such as price and brand name will affect the therapeutic efficacy of an analgesic, i.e. a medicine will have greater influence when the patient is aware of its price compared to one who is not.
|Condition or disease||Intervention/treatment||Phase|
|Pain||Drug: High price Drug: Low price Drug: Low price participants aware paying part Drug: No price Drug: Free of charge||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||220 participants|
|Intervention Model:||Parallel Assignment|
|Official Title:||The Effect of Price and Marketing Variable on the Pain Controlling Effect of Active Drugs in a Clinical Trial.|
|Study Start Date :||January 2012|
|Estimated Primary Completion Date :||December 2012|
|Estimated Study Completion Date :||June 2013|
|Active Comparator: High price||
Drug: High price
Acetaminophen label as high price
|Active Comparator: Low price||
Drug: Low price
Acetaminophen label as low price
|Active Comparator: Low price participants aware paying part||
Drug: Low price participants aware paying part
Acetaminophen label as low price; participants aware they are paying part of the full price
|Active Comparator: No price||
Drug: No price
acetaminophen. No price - price issue not introduced to participants.
|Active Comparator: Free of charge||
Drug: Free of charge
Acetaminophen. participants aware the product is free of charge
- pain thresholds [ Time Frame: 1hour ]Participants will rank their pain thresholds individually and subjectively for a series of pulses. Each participant will experience a series of pulses with random intensity. Pulse intensity will range within 30-90% of the participants maximal level.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01493908
|Contact: Amnon - Lahad, MD, MPHfirstname.lastname@example.org|
|Contact: Hadas - Lemberg, PhD||00 972 2 email@example.com|
|Department of Family Medicine, Hebrew University, JerusaelmIsrael||Not yet recruiting|
|Jerusalem, Israel, 91120|
|Contact: Amnon - Lahad, MD, MPH +972-2-758505 firstname.lastname@example.org|
|Contact: Hadas Lemberg, PhD 00 972 2 6777572 email@example.com|
|Principal Investigator: Lahad - Amnon, MD, MPH|
|Principal Investigator:||Amnon - Lahad, MD, MPH||Hebrew University, Jerusalem Israel|