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The Effect of Acupuncture on Anxiety and Working Memory

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT01492738
Recruitment Status : Completed
First Posted : December 15, 2011
Last Update Posted : April 15, 2015
Information provided by (Responsible Party):

Study Description
Brief Summary:
This study endeavors to examine the relationship between acupuncture, anxiety, and performance on a test of working memory. In the study, all participants will complete the State-Trait Anxiety Inventory (STAI) survey to determine how anxious they are at the moment and how anxious they tend to be in general. Then ½ of subjects will receive acupuncture for 20 minutes and ½ will rest quietly for 20 minutes. After this period, all subjects will again complete the STAI survey. Then all subjects will complete the Automated Operations Span Task (AOSPAN) which is a computerized test of working memory. Statistical analysis will be performed to determine if acupuncture had any effect on State-level anxiety and on performance on the AOSPAN.

Condition or disease Intervention/treatment
Memory Impairment Anxiety Procedure: Acupuncture

Study Design

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 90 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: The Effect of Acupuncture on Anxiety and Working Memory
Study Start Date : February 2011
Primary Completion Date : December 2011
Study Completion Date : December 2011

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Arms and Interventions

Arm Intervention/treatment
No Intervention: Control Group
Participants will be asked to make themselves comfortable lying on a massage table for 20 minutes.
Active Comparator: Acupuncture group
Acupuncture group will receive one acupuncture treatment for twenty minutes.
Procedure: Acupuncture
After completing questionnaires and anxiety survey, a licensed acupuncturist will insert needles according to Clean Needle Technique into specific acupuncture points. Procedure will last 20 minutes.Following acupuncture treatment, participants will complete anxiety survey and memory test.

Outcome Measures

Primary Outcome Measures :
  1. Change in anxiety level [ Time Frame: Baseline and after1 hour ]
    Participants will complete the State-Trait Anxiety Inventory survey to see how anxious they are initially; after acupuncture treatment or quiet resting, they will complete the survey again to see how anxious they are after the intervention.

  2. Memory task [ Time Frame: After 1 hour ]
    Following acupuncture treatment or resting control, participants will complete a standardized memory test (AOSPAN) to see if intervention affects memory.

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 30 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Undergraduate University student
  • Fluent in English
  • Willing to receive acupuncture
  • Aged 18-30
  • In good health
  • Not pregnant
  • Not breastfeeding

Exclusion Criteria:

  • Not an Undergraduate University student
  • Not fluent in English
  • Unwilling to receive acupuncture
  • Under 18 years of age or older than 30 years of age
  • Chronic disease
  • Pregnant
  • Breastfeeding
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01492738

United States, Illinois
Tiffani Kim Institute
Chicago, Illinois, United States, 60654
A Center for Oriental Medicine
Wilmette, Illinois, United States, 60091
Sponsors and Collaborators
National University of Health Sciences
Principal Investigator: Jason Bussell, MSOM, LAc National University of Health Sciences
Study Director: Hui Yan Cai, PhD, LAc National University of Health Sciences
More Information

Responsible Party: National University of Health Sciences
ClinicalTrials.gov Identifier: NCT01492738     History of Changes
Other Study ID Numbers: NUHS H1011
First Posted: December 15, 2011    Key Record Dates
Last Update Posted: April 15, 2015
Last Verified: April 2015

Keywords provided by National University of Health Sciences:

Additional relevant MeSH terms:
Anxiety Disorders
Mental Disorders