Brain Lesions Following Endovascular and Surgical Treatment of Unruptured Intracranial Aneurysms (LESUIA)
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government.
Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT01490463
Recruitment Status :
First Posted : December 13, 2011
Last Update Posted : January 30, 2013
Johann Wolfgang Goethe University Hospital
Department of Neurosurgery, Goethe-University Frankfurt am Main
Institute of Neuroradiology, Goethe-University Frankfurt am Main
Information provided by (Responsible Party):
Erdem Güresir, Johann Wolfgang Goethe University Hospital
The purpose of this study is to determine the incidence and impact of brain lesions in MRI after coiling and clipping of unruptured intracranial aneurysms on clinical and neurological outcome of patients.
Condition or disease
Unruptured Intracranial Aneurysms
Silent ischemic lesions after treatment of unruptured intracranial aneurysm (UIA) might alter patients' clinical and neurological outcome. Furthermore silent brain lesions are not well documented after endovascular and surgical treatment of unruptured intracranial aneurysms. Therefore, the investigators investigate the incidence and influence of treatment-related ischemic lesions in magnetic resonance / diffusion-weighted-imaging after endovascular and surgical treatment of UIA.
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study:
18 Years to 80 Years (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Patients with unruptured intracranial aneurysm undergoing endovascular or surgical treatment
diagnosis and treatment of unruptured intracranial aneurysm
age ≥ 18 yrs
written informed consent by patients prior to study participation