Wind Instruments' Fungal Contamination

This study has been completed.

Sponsor:

ClinicalTrials.gov Identifier:

NCT01487850

First Posted: December 8, 2011

Last Update Posted: December 9, 2011

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.

Information provided by (Responsible Party):

Flora METZGER, Centre Hospitalier Universitaire de Besancon

Purpose

On the basis of 2 cases of immunologically-induced lung disease in 2 saxophonists, the investigators supposed that wind reed instruments could be contaminated with molds. The investigators led a study on 40 musicians playing a wind reed instrument to analyze instruments' fungal contamination and its immunological and clinical consequences for musicians.

Condition	Intervention
Immunologically-induced Lung Disease Hypersensitivity Pneumonitis	Biological: blood sample


Study Type:	Interventional
Study Design:	Primary Purpose: Diagnostic
Official Title:	Study of Wind Reed Instruments' Fungal Contamination and Its Immunological and Clinical Consequences for Musicians.

Resource links provided by NLM:

MedlinePlus related topics: Gas Molds

Genetic and Rare Diseases Information Center resources: Hypersensitivity Pneumonitis

U.S. FDA Resources

Further study details as provided by Flora METZGER, Centre Hospitalier Universitaire de Besancon:


Study Start Date:	May 2007
Study Completion Date:	October 2007
Primary Completion Date:	June 2007 (Final data collection date for primary outcome measure)

Intervention Details:

blood sample in each musician to search for specific antibodies against molds isolated from instruments

Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:	18 Years and older (Adult, Senior)
Sexes Eligible for Study:	All
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

must be 18 year old or more
must play a wind reed instrument (saxophone, clarinet, bassoon or oboe) one hour per week or more

Exclusion Criteria:

refuse to sign consent

Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01487850

Locations


France
Centre Hospitalier Universitaire Saint Jacques
Besancon, Franche Comté, France, 25000

Sponsors and Collaborators

Centre Hospitalier Universitaire de Besancon

More Information

Publications:

Lodha S, Sharma OP. Hypersensitivity pneumonitis in a saxophone player. Chest. 1988 Jun;93(6):1322.

Metzger F, Haccuria A, Reboux G, Nolard N, Dalphin JC, De Vuyst P. Hypersensitivity pneumonitis due to molds in a saxophone player. Chest. 2010 Sep;138(3):724-6. doi: 10.1378/chest.09-2991.


Responsible Party:	Flora METZGER, Medical Doctor, Lung specialist, Principal Investigator, Centre Hospitalier Universitaire de Besancon
ClinicalTrials.gov Identifier:	NCT01487850 History of Changes
Other Study ID Numbers:	P/2007/55
First Submitted:	December 6, 2011
First Posted:	December 8, 2011
Last Update Posted:	December 9, 2011
Last Verified:	December 2011

Keywords provided by Flora METZGER, Centre Hospitalier Universitaire de Besancon:


wind instruments molds hypersensitivity pneumonitis	fungal contamination of wind instruments specific antibodies against molds in musicians' sera musicians

Additional relevant MeSH terms:


Lung Diseases Hypersensitivity Pneumonia Alveolitis, Extrinsic Allergic Respiratory Tract Diseases	Immune System Diseases Respiratory Tract Infections Lung Diseases, Interstitial Respiratory Hypersensitivity Hypersensitivity, Immediate

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