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A Pilot Study to Evaluate Multi-Spectral Imaging and Laser Speckle Imaging During Vascular Occlusion

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ClinicalTrials.gov Identifier: NCT01484730
Recruitment Status : Withdrawn
First Posted : December 2, 2011
Last Update Posted : September 19, 2017
Sponsor:
Collaborator:
Beckman Laser Institute University of California Irvine
Information provided by (Responsible Party):
Beckman Laser Institute and Medical Center, University of California, Irvine

Brief Summary:
The purpose of this research is to evaluate and validate the performance of non-invasive imaging modalities for assessment of skin. A pressure cuff occlusion will be used to stimulate blood flow dynamic that these instruments are designed to sense. The researcher currently plan to assess only basic feasibility of the imaging instruments.

Condition or disease Intervention/treatment
Abnormal Vascular Flow Device: Multi-Spectral & Laser Speckle Imaging

Detailed Description:

The primary reason for including pressure cuff occlusion in this protocol is to test the performance of Multi-Spectral Imaging and Laser Speckle Imaging can measure in the full range of vascular conditions ranging from ischemic (under-perfused or unsaturated) to hyperemic (over-perfused and over-saturated).

  1. .Modulated Imaging a non-contact optical imaging technology can detect the concentration of total hemoglobin, deoxygenated and oxygenated hemoglobin in absolute amounts in units of millimoles / unit volume of tissue measured.
  2. . Laser Speckle Imaging a non-contact optical imaging technology consists of a coherent light source, camera, and image acquisition system. This image device can measure and compare relative flow in vasculature at varied time points.

Study Type : Observational
Actual Enrollment : 0 participants
Observational Model: Case-Only
Time Perspective: Cross-Sectional
Official Title: A Pilot Study to Evaluate Multi-Spectral Imaging and Laser Speckle Imaging During Vascular Occlusion
Study Start Date : November 2011
Estimated Primary Completion Date : November 2018
Estimated Study Completion Date : November 2018

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Group/Cohort Intervention/treatment
Vascular Occulsion
Multi-Spectral & Laser Speckle Imaging
Device: Multi-Spectral & Laser Speckle Imaging
Changes in skin tissue and blood flow.



Primary Outcome Measures :
  1. Skin blood flow [ Time Frame: 4 weeks ]


Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Study population will be selected from University of California Irvine, student and staff member.
Criteria

Inclusion Criteria:

  • Male and female adult 18 years and older

Exclusion Criteria:

  • Younger than 18 years of age
  • Pregnant women

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01484730


Locations
United States, California
Beckman Laser Institute, UCI
Irvine, California, United States, 92612
Sponsors and Collaborators
University of California, Irvine
Beckman Laser Institute University of California Irvine
Investigators
Principal Investigator: Anthony Durkin, PhD Beckman Laser Institute, UCI

Responsible Party: Beckman Laser Institute and Medical Center, Anthony Durkin, Ph.D. Associate Professor, Director, Laboratory for Functional Imaging and Spectroscopy of Superficial Tissues, University of California, Irvine
ClinicalTrials.gov Identifier: NCT01484730     History of Changes
Other Study ID Numbers: NIH/LAMMP-2011-8370
First Posted: December 2, 2011    Key Record Dates
Last Update Posted: September 19, 2017
Last Verified: September 2017