Treatments of Acquired Apraxia of Speech (Apraxia)

This study is ongoing, but not recruiting participants.
Information provided by (Responsible Party):
VA Office of Research and Development Identifier:
First received: April 15, 2011
Last updated: November 6, 2015
Last verified: November 2015
This study is designed to examine the effects of speech therapy on ability to produce speech sounds in persons with acquired apraxia of speech.

Condition Intervention Phase
Apraxia of Speech
Behavioral: Sound Production Treatment
Phase 1

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Crossover Assignment
Masking: Single Blind (Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Treatments of Acquired Apraxia of Speech

Resource links provided by NLM:

Further study details as provided by VA Office of Research and Development:

Primary Outcome Measures:
  • speech production [ Time Frame: Pre treatment (2-3 week period preceding the start of treatment) , Interim treatment (after 20 treatment session - approximately 7 weeks after the start of treatment), and Post treatment (after another 20 treatment sessions - approximately 15 weeks) ] [ Designated as safety issue: No ]
    accuracy of articulation

Estimated Enrollment: 24
Study Start Date: August 2011
Estimated Study Completion Date: March 2016
Estimated Primary Completion Date: January 2016 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Arm 1
two groups will receive treatment
Behavioral: Sound Production Treatment
A treatment for acquired apraxia of speech. Combines therapist modeling, simultaneous production, articulatory instruction, feedback and repeated practice

Detailed Description:
This study is designed to investigate the effects of Sound Production Treatment (SPT; a treatment for acquired apraxia of speech) on sound production accuracy in persons with chronic apraxia of speech (AOS). Organization of practice (blocked practice or randomized practice) will be manipulated in an effort to determine the most efficacious application of SPT. A combination of group and single-subject experimental designs will be completed with 24 speakers with AOS (2 groups of 12 participants).

Ages Eligible for Study:   21 Years to 85 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Must have acquired apraxia of speech that occurred following a stroke or other brain injury.
  • Must be at least 6 months post-onset of brain injury.
  • May have aphasia.

Exclusion Criteria:

  • History of drug or alcohol abuse.
  • History of mental illness.
  • Neurological condition other than that which resulted in apraxia of speech.
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Please refer to this study by its identifier: NCT01483807

United States, Utah
VA Salt Lake City Health Care System, Salt Lake City, UT
Salt Lake City, Utah, United States, 84148
Sponsors and Collaborators
VA Office of Research and Development
Principal Investigator: Julie L Wambaugh, PhD VA Salt Lake City Health Care System, Salt Lake City, UT
  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: VA Office of Research and Development Identifier: NCT01483807     History of Changes
Other Study ID Numbers: C7419-R 
Study First Received: April 15, 2011
Last Updated: November 6, 2015
Health Authority: United States: Federal Government

Keywords provided by VA Office of Research and Development:
speech therapy
apraxia of speech

Additional relevant MeSH terms:
Nervous System Diseases
Neurobehavioral Manifestations
Neurologic Manifestations
Psychomotor Disorders
Signs and Symptoms processed this record on May 01, 2016