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Vascular Occlusion in Patients With Osteoarthritis

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified February 2014 by Bruno Gualano, University of Sao Paulo.
Recruitment status was:  Recruiting
Sponsor:
ClinicalTrials.gov Identifier:
NCT01483131
First Posted: December 1, 2011
Last Update Posted: February 28, 2014
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Bruno Gualano, University of Sao Paulo
  Purpose
Resistance exercise plus vascular occlusion may induce greater improvements in strength and muscle mass than resistance training alone. The investigators speculate this training strategy could be beneficial in patients with osteoarthritis.

Condition Intervention
Osteoarthritis Other: Exercise training Other: Resistance training with vascular occlusion

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Effects of Strength Training Associated With Vascular Occlusion in Patients With Knee Osteoarthritis

Resource links provided by NLM:


Further study details as provided by Bruno Gualano, University of Sao Paulo:

Primary Outcome Measures:
  • muscle strength [ Time Frame: 12 weeks ]

Secondary Outcome Measures:
  • Quality of Life [ Time Frame: 12 weeks ]

Estimated Enrollment: 45
Study Start Date: November 2011
Estimated Study Completion Date: December 2014
Primary Completion Date: November 2013 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Low intensity resistance training Other: Exercise training
12 weeks of resistance training twice a week.
Experimental: High intensity resistance training Other: Exercise training
12 weeks of resistance training twice a week.
Experimental: Low intensity resistance training with vascular occlusion Other: Resistance training with vascular occlusion
12 weeks of resistance training with vascular occlusion twice a week

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   50 Years to 65 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Postmenopausal women
  • BMI <39
  • Knee Ostearthritis type II and III
  • VAS (visual analogue scale) between 2 and 8

Exclusion Criteria:

  • Hip osteoarthritis
  • Use of NSAID
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01483131


Contacts
Contact: Rodrigo Ferraz, Msc 55 11 8122 1203 ferraz@email.com

Locations
Brazil
University of Sao Paulo -School of Medicine - Clinical Hospital Recruiting
Sao Paulo, Brazil, 05403 010
Contact: Rodrigo Ferraz, Msc    55 11 8122 1203    ferraz@email.com   
Principal Investigator: Hamilton Roschel, PhD         
Principal Investigator: Ana Lucia Sá Pinto, PhD         
Sub-Investigator: Bruno Gualano, PhD         
Sponsors and Collaborators
University of Sao Paulo
  More Information

Responsible Party: Bruno Gualano, Professor, University of Sao Paulo
ClinicalTrials.gov Identifier: NCT01483131     History of Changes
Other Study ID Numbers: vascular occlusion and OA
First Submitted: November 29, 2011
First Posted: December 1, 2011
Last Update Posted: February 28, 2014
Last Verified: February 2014

Additional relevant MeSH terms:
Osteoarthritis
Arthritis
Joint Diseases
Musculoskeletal Diseases
Rheumatic Diseases