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Vascular Occlusion in Patients With Osteoarthritis

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ClinicalTrials.gov Identifier: NCT01483131
Recruitment Status : Unknown
Verified February 2014 by Bruno Gualano, University of Sao Paulo.
Recruitment status was:  Recruiting
First Posted : December 1, 2011
Last Update Posted : February 28, 2014
Sponsor:
Information provided by (Responsible Party):
Bruno Gualano, University of Sao Paulo

Brief Summary:
Resistance exercise plus vascular occlusion may induce greater improvements in strength and muscle mass than resistance training alone. The investigators speculate this training strategy could be beneficial in patients with osteoarthritis.

Condition or disease Intervention/treatment Phase
Osteoarthritis Other: Exercise training Other: Resistance training with vascular occlusion Not Applicable

Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 45 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Effects of Strength Training Associated With Vascular Occlusion in Patients With Knee Osteoarthritis
Study Start Date : November 2011
Actual Primary Completion Date : November 2013
Estimated Study Completion Date : December 2014

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Osteoarthritis
U.S. FDA Resources

Arm Intervention/treatment
Experimental: Low intensity resistance training Other: Exercise training
12 weeks of resistance training twice a week.
Experimental: High intensity resistance training Other: Exercise training
12 weeks of resistance training twice a week.
Experimental: Low intensity resistance training with vascular occlusion Other: Resistance training with vascular occlusion
12 weeks of resistance training with vascular occlusion twice a week



Primary Outcome Measures :
  1. muscle strength [ Time Frame: 12 weeks ]

Secondary Outcome Measures :
  1. Quality of Life [ Time Frame: 12 weeks ]


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Ages Eligible for Study:   50 Years to 65 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Postmenopausal women
  • BMI <39
  • Knee Ostearthritis type II and III
  • VAS (visual analogue scale) between 2 and 8

Exclusion Criteria:

  • Hip osteoarthritis
  • Use of NSAID

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01483131


Contacts
Contact: Rodrigo Ferraz, Msc 55 11 8122 1203 ferraz@email.com

Locations
Brazil
University of Sao Paulo -School of Medicine - Clinical Hospital Recruiting
Sao Paulo, Brazil, 05403 010
Contact: Rodrigo Ferraz, Msc    55 11 8122 1203    ferraz@email.com   
Principal Investigator: Hamilton Roschel, PhD         
Principal Investigator: Ana Lucia Sá Pinto, PhD         
Sub-Investigator: Bruno Gualano, PhD         
Sponsors and Collaborators
University of Sao Paulo

Responsible Party: Bruno Gualano, Professor, University of Sao Paulo
ClinicalTrials.gov Identifier: NCT01483131     History of Changes
Other Study ID Numbers: vascular occlusion and OA
First Posted: December 1, 2011    Key Record Dates
Last Update Posted: February 28, 2014
Last Verified: February 2014

Additional relevant MeSH terms:
Osteoarthritis
Arthritis
Joint Diseases
Musculoskeletal Diseases
Rheumatic Diseases