We are updating the design of this site. Learn more.
Show more
ClinicalTrials.gov
ClinicalTrials.gov Menu

Effect of Body Composition and Metabolism on Oocyte Gene Expression

This study is ongoing, but not recruiting participants.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01480024
First Posted: November 28, 2011
Last Update Posted: June 29, 2017
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Arkansas Children's Hospital Research Institute
  Purpose
The investigators will test the hypothesis that obese women have a unique oocyte gene expression profile that differs significantly from that of normal weight women.

Condition
Healthy

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Effect of Body Composition and Metabolism on Oocyte Gene Expression

Resource links provided by NLM:


Further study details as provided by Arkansas Children's Hospital Research Institute:

Primary Outcome Measures:
  • oocyte gene expression profile [ Time Frame: 1-2 weeks ]

Biospecimen Retention:   Samples With DNA
oocytes and follicular fluid

Estimated Enrollment: 70
Study Start Date: April 2011
Estimated Study Completion Date: May 2018
Estimated Primary Completion Date: December 2017 (Final data collection date for primary outcome measure)
  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years to 38 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
women of childbearing age undergoing fertility treatment
Criteria

Inclusion Criteria:

  • BMI < 25 (N=35) or BMI ≥ 30 (N=35)
  • Seeking fertility treatment at the Arkansas Fertility and Gynecology Associates Clinic
  • Assisted reproduction will include the oocyte retrieval technique
  • 18 to 38 years of age

Exclusion Criteria:

  • Any health condition or medication that may interfere with the study outcome as determined by the investigators
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01480024


Locations
United States, Arkansas
Arkansas Children's Nutrition Center
Little Rock, Arkansas, United States, 72202
Sponsors and Collaborators
Arkansas Children's Hospital Research Institute
  More Information

Responsible Party: Arkansas Children's Hospital Research Institute
ClinicalTrials.gov Identifier: NCT01480024     History of Changes
Other Study ID Numbers: 131386
First Submitted: November 23, 2011
First Posted: November 28, 2011
Last Update Posted: June 29, 2017
Last Verified: June 2017

Keywords provided by Arkansas Children's Hospital Research Institute:
healthy women
oocytes
in vitro fertilization
pregnancy
childbearing-age