PEEP Recruitment-comparison Between Ultrasonographic Assessment and LIP Assessment
The purpose of this study is to compare lung recruitment in acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) based on lower inflection point with transthoracic ultrasonographic assessment of lung recruitment.
Acute Respiratory Distress Syndrome
|Study Design:||Observational Model: Case Control|
|Official Title:||Positive End-expiratory Pressure Induced Lung Recruitment -Comparison Between Ultrasonographic Assessment and Lower Inflection Point Assessment on the Pressure -Volume Loop|
|Study Start Date:||October 2009|
|Study Completion Date:||November 2011|
|Primary Completion Date:||November 2011 (Final data collection date for primary outcome measure)|
Sedated and sometimes temporary relaxed patients with ALI/ARDS on mechanical ventilation in semirecumbent position are included. Lower inflection point on pressure volume loop on ventilator Draeger Evita 4 with low continuous flow on volume controlled ventilation is measured with zero PEEP. Transthoracic lung ultrasound with linear probe is proceed on both hemithoraces when mechanical ventilation based on measured PEEP is started. We compare if real lung recruitment seen by ultrasound is the same as predicted by lower inflection point.
The procedure is a part of routine everyday respiratory monitoring in our unit.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01478217
|Central intensive care unit, University hospital "Sisters of Mercy"|
|Grad Zagreb, Croatia, 10000|
|Principal Investigator:||Bojan Rode, M.D.|