Efficacy of an Extract of Concentrated Korean Red Ginseng for Preventing Upper Respiratory Tract Infections
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|ClinicalTrials.gov Identifier: NCT01478009|
Recruitment Status : Completed
First Posted : November 23, 2011
Results First Posted : December 25, 2012
Last Update Posted : December 25, 2012
|Condition or disease||Intervention/treatment||Phase|
|Healthy Subjects||Dietary Supplement: Korean red ginseng Dietary Supplement: Placebo||Phase 2 Phase 3|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||100 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Double (Participant, Investigator)|
|Official Title:||A Placebo-Controlled Trial of Korean Red Ginseng Extract to Prevent Acute Respiratory Illness in Healthy Subjects|
|Study Start Date :||November 2010|
|Actual Primary Completion Date :||December 2011|
|Actual Study Completion Date :||December 2011|
|Experimental: KRG Extract||
Dietary Supplement: Korean red ginseng
Korean red ginseng(3.0g/day) for 12 weeks
|Placebo Comparator: Placebo||
Dietary Supplement: Placebo
Placebo (3.0g/day) for 12 weeks
- Frequency of ILI(Influenza Like Illness) [ Time Frame: 12 weeks ]Subjects received the open-ended questions about frequency of ILI onset during study period. The frequency of ILI onset was checked weekly via telephone.
- Symptom Severity of All Colds [ Time Frame: 12 weeks ]
Subjects received the open-ended questions about symptom severity of all colds onset during study period. The symptom severity of all colds onset was checked weekly via telephone.
Symptom severity of all colds (score 0-27) was measured during study period. The original index consists of 9 Questions(Fever, Rhinorrhea, Nasal congestion, Sore throat, Cough, Sputum, Dyspnea, Headache, Myalgia).
Individual question response is assigned a score of between 0 (none) to 3 (severe) and summed to form a total score(summed) ranging from 0 (best) to 27 (worst).
- Total Number of Days of Symptoms and Duration of All Colds [ Time Frame: up to 12 weeks ]Extract of Korean red ginseng intake did not significantly reduced total number of days of symptoms and duration of all colds
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01478009
|Korea, Republic of|
|Clinical Trial Center for Functional Foods; Chonbuk National University Hospital|
|Jeonju, Jeollabuk-do, Korea, Republic of, 560-822|
|Principal Investigator:||Chang-Seop Lee, MD||Chonbuk National University Hospital|