We are updating the design of this site. Learn more.
Show more
ClinicalTrials.gov
ClinicalTrials.gov Menu

Toothbrushing and Ventilator-associated Pneumonia

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01477099
First Posted: November 22, 2011
Last Update Posted: November 22, 2011
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Miriam Cervino, Hospital Universitario de Canarias
  Purpose
The hypothesis is that adding the toothbrushing to the oral care with clorhexidine 0.12% could be reduce the incidence of ventilator-associated pneumonia due to that oral cavity may be an important reservoir of pathogens that could cause pneumonia.

Condition Intervention Phase
Ventilator Associated Pneumonia Device: Toothbrushing with a manual brush Phase 4

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Prevention
Official Title: Efficacy of Toothbrushing for the Prevention of Ventilator-associated Pneumonia

Resource links provided by NLM:


Further study details as provided by Miriam Cervino, Hospital Universitario de Canarias:

Primary Outcome Measures:
  • Prevention of ventilator-associated pneumonia [ Time Frame: 60 days ]

Enrollment: 436
Study Start Date: August 2010
Study Completion Date: August 2011
Primary Completion Date: August 2011 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Toothbrushing with a manual brush
Toothbrushing with a manual brush
Device: Toothbrushing with a manual brush
Toothbrushing with a manual brush
No Intervention: No toothbrushing
no toothbrushing

  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • mechanical ventilation

Exclusion Criteria:

  • edentulous
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01477099


Locations
Spain
Leonardo Lorente
La Laguna, Tenerife, Spain, 38320
Sponsors and Collaborators
Hospital Universitario de Canarias
Investigators
Principal Investigator: Leonardo Lorente, Medical Hospital Universitario de Canarias
  More Information

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Miriam Cervino, Medical Doctor, Hospital Universitario de Canarias
ClinicalTrials.gov Identifier: NCT01477099     History of Changes
Other Study ID Numbers: BRUSH-2009
First Submitted: November 16, 2011
First Posted: November 22, 2011
Last Update Posted: November 22, 2011
Last Verified: November 2011

Additional relevant MeSH terms:
Pneumonia
Pneumonia, Ventilator-Associated
Lung Diseases
Respiratory Tract Diseases
Respiratory Tract Infections
Cross Infection
Infection
Ventilator-Induced Lung Injury
Lung Injury